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Kohei Hasegawa, MD, MPH, Department of Emergency Medicine, Massachusetts General Hospital, 125 Nashua Street, Suite 920, Boston, MA 02114, USA. Email: E-mail address:khasegawa1@partners.org
KH carried out the statistical analysis, drafted the initial manuscript, and approved the final manuscript as submitted.
RWL conceptualized and designed the study, enrolled the subjects, drafted the initial manuscript, and approved the final manuscript as submitted.
JMM and CAC conceptualized and designed the study, obtained the funding, reviewed and revised the manuscript, and approved the final manuscript as submitted.
NJA and JFP generated the microbiome data, carried out the initial statistical analysis, reviewed and revised the manuscript, and approved the final manuscript as submitted.
RGF was involved in the patient enrollment, critically reviewed and revised the manuscript, and approved the final manuscript as submitted.
JAE carried out the initial analyses, reviewed and revised the manuscript, and approved the final manuscript as submitted.
The authors thank Pedro A. Piedra, MD (Baylor College of Medicine), Ashley F. Sullivan, MS, MPH (Massachusetts General Hospital), the staff at the Massachusetts General Hospital Pediatric Group Practice, and all of the study families for their contributions to the study.
The content of this manuscript is solely the responsibility of the authors and does not necessarily represent the official views of the National Institutes of Health.
Drs. Ajami and Petrosino own shares of Diversigen Inc., a microbiome research company.
The other authors have no financial relationships relevant to this article to disclose.
This study was supported by the grants U01 AI-087881, R01 AI-114552, R01 AI-108588, and R21 HL-129909 from the National Institutes of Health (Bethesda, MD).
© 2016 Japan Pediatric Society