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Author Notes:

Sandra Weintraub, PhD, Cognitive Neurology and Alzheimer’s Disease Center, Northwestern University Feinberg School of Medicine (e-mail: sweintraub@northwestern.edu).

The Uniform Data Set Neuropsychology Work Group dedicates this paper to the memory of Dr Steven Ferris, who passed away on April 5, 2017.

He was a cherished and highly respected member of our community who made major contributions to the creation of the UDS and to the work that went into this publication.

We all mourn his loss.

The Uniform Data Set Neuropsychology Work Group wishes to thank the following individuals for giving their permission to include tests they created in the UDSNB 3.0: Zaid Nasreddine, MD (MoCA); Suzanne Craft, PhD (“Craft Story” and scoring method); Andrew Saykin, PhD for providing data on the equivalence of forms of the Craft Story to Logical Memory; Tamar Gollan, PhD for the MINT; Joel Kramer for providing alternate number strings for the number span test; and Kate Possin and Joel Kramer for the Benson complex figure test.

We also wish to thank Nina Silverberg, PhD, for her insightful leadership throughout the conduct of this project.

See publication for complete list of disclosures.

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Research Funding:

The NACC database is funded by NIA/NIH Grant U01 AG016976.

NACC data are contributed by the NIA-funded ADCs: P30 AG019610 (PI Eric Reiman, MD), P30 AG013846 (PI Neil Kowall, MD), P50 AG008702 (PI Scott Small, MD), P50 AG025688 (PI Allan Levey, MD, PhD), P50 AG047266 (PI Todd Golde, MD, PhD), P30 AG010133 (PI Andrew Saykin, PsyD), P50 AG005146 (PI Marilyn Albert, PhD), P50 AG005134 (PI Bradley Hyman, MD, PhD), P50 AG016574 (PI Ronald Petersen, MD, PhD), P50 AG005138 (PI Mary Sano, PhD), P30 AG008051 (PI Thomas Wisniewski, MD), P30 AG013854 (PI M. Marsel Mesulam, MD), P30 AG008017 (PI Jeffrey Kaye, MD), P30 AG010161 (PI David Bennett, MD), P50 AG047366 (PI Victor Henderson, MD, MS), P30 AG010129 (PI Charles DeCarli, MD), P50 AG016573 (PI Frank LaFerla, PhD), P50 AG005131 (PI James Brewer, MD, PhD), P50 AG023501 (PI Bruce Miller, MD), P30 AG035982 (PI Russell Swerdlow, MD), P30 AG028383 (PI Linda Van Eldik, PhD), P30 AG053760 (PI Henry Paulson, MD, PhD), P30 AG010124 (PI John Trojanowski, MD, PhD), P50 AG005133 (PI Oscar Lopez, MD), P50 AG005142 (PI Helena Chui, MD), P30 AG012300 (PI Roger Rosenberg, MD), P30 AG049638 (PI Suzanne Craft, PhD), P50 AG005136 (PI Thomas Grabowski, MD), P50 AG033514 (PI Sanjay Asthana, MD, FRCP), P50 AG005681 (PI John Morris, MD), P50 AG047270 (PI Stephen Strittmatter, MD, PhD).

Keywords:

  • Science & Technology
  • Life Sciences & Biomedicine
  • Clinical Neurology
  • Pathology
  • Neurosciences & Neurology
  • dementia
  • neuropsychological test
  • cognition
  • UDS
  • MONTREAL COGNITIVE ASSESSMENT
  • POSTERIOR CORTICAL ATROPHY
  • CENTER NACC DATABASE
  • ASSESSMENT MOCA
  • OLDER-ADULTS
  • IMPAIRMENT
  • DEMENTIA
  • MEMORY
  • VALIDATION
  • VALIDITY

Version 3 of the Alzheimer Disease Centers’ Neuropsychological Test Battery in the Uniform Data Set (UDS)

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Journal Title:

Alzheimer Disease and Associated Disorders

Volume:

Volume 32, Number 1

Publisher:

, Pages 10-17

Type of Work:

Article | Final Publisher PDF

Abstract:

The neuropsychological battery of the Uniform Data Set (UDSNB) was implemented in 2005 by the National Institute on Aging (NIA) Alzheimer Disease Centers program to measure cognitive performance in dementia and mild cognitive impairment due to Alzheimer Disease. This paper describes a revision, the UDSNB 3.0. Methods: The Neuropsychology Work Group of the NIA Clinical Task Force recommended revisions through a process of due diligence to address shortcomings of the original battery. The UDSNB 3.0 covers episodic memory, processing speed, executive function, language, and constructional ability. Data from 3602 cognitively normal participants in the National Alzheimer Coordinating Center database were analyzed. Results: Descriptive statistics are presented. Multivariable linear regression analyses demonstrated score differences by age, sex, and education and were also used to create a normative calculator available online. Discussion: The UDSNB 3.0 neuropsychological battery provides a valuable non proprietary resource for conducting research on cognitive aging and dementia.

Copyright information:

© 2017 The Author(s). Published by Wolters Kluwer Health, Inc.

This is an Open Access work distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License (http://creativecommons.org/licenses/by-nc-nd/4.0/).

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