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Correspondence and requests for materials should be addressed to N.P.P. (email: npeders@emory.edu) or to P.M.F. (email: pfuller@bidmc.harvard.edu)
Clifford B. Saper and Patrick M. Fuller contributed equally to this work.
N.P.P., N.V., E.A., P.M.F. and C.B.S. were responsible for study inception and design of experiments.
N.P.P., L.F., J.L.W., A.V., S.B.A., E.A. and P.M.F. performed experiments.
N.P.P., L.F., J.L.W., A.V., S.B.A., E.A., P.M.F. and C.B.S. analyzed or interpreted data.
N.P.P., E.A., P.M.F. and C.B.S. wrote the paper.
We are grateful for the technical assistance of Quan Hue Ha, Minh Ha, Sarah Keating, Myriam Debryune, and Rebecca Broadhurst, and for the kind gift, from Drs Bradford Lowell and Linh Vong, of Vgat-IRES-cre and Vglut2-IRES-cre lines of mice.
The authors declare no competing financial interests.
Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.
This work was supported by the National Institutes of Health R25NS070682 and an American Academy of Neurology and American Brain Foundation Clinician-Researcher Training Fellowship (N.P.P.), as well as NARSAD Young Investigator Grant (A.V.), National Health and Medical Research Council of Australia Early Career Fellowship GNT1052674 (S.B.G.A.).
National Health and Medical Research Council C.J. Martin Award (S.B.G.A.), National Institutes of Health grants R21NS082854 (E.A.), R01NS073613 (P.M.F.), R01NS092652 (P.M.F.), R01NS085477 (C.B.S.), and P01HL095491 (C.B.S., E.A.).
© 2017 The Author(s).