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Author Notes:

Corresponding author: Sophia A. Hussen, Hubert Department of Global Health, 1518 Clifton Road NE Mailstop: 1518-002-7BB, Atlanta, GA 30322, USA. (Sophia.ahmed.hussen@emory.edu)

S.A.H. conceived the study and drafted the manuscript.

R.C. contributed to study conception, interpretation of data and manuscript revisions.

A.K. contributed to data analysis and revising the manuscript.

A.C.G. contributed to interpretation of data and manuscript revisions.

E.H. contributed to data analysis and revising the manuscript.

R.S. contributed to study conception and revising the manuscript.

C.D.R. contributed to study conception, interpretation of data and revising the manuscript.

All authors have read and approved the final version of the manuscript prior to submission.

We would like to acknowledge the work of graduate research assistants Sonam Patel, Zelalem Adefris and Emily Grossniklaus, who assisted with data abstraction.

The authors have no competing interests to declare.

Subjects:

Research Funding:

This work was supported by a grant from the Emory Medical Care Foundation to S.A.H. S.A.H.'s work on this manuscript is also supported by the Harold Amos Medical Faculty Development Program of the Robert Wood Johnson Foundation [Grant# 73309].

Keywords:

  • Science & Technology
  • Life Sciences & Biomedicine
  • Immunology
  • Infectious Diseases
  • adolescent
  • transition
  • HIV
  • care engagement
  • continuum
  • engagement
  • youth
  • PERINATALLY ACQUIRED HIV
  • INFECTED ADOLESCENTS
  • HEALTH-CARE
  • YOUTH
  • EXPERIENCE
  • MEDICINE
  • SERVICES

Transitioning young adults from paediatric to adult care and the HIV care continuum in Atlanta, Georgia, USA: a retrospective cohort study

Tools:

Journal Title:

Journal of the International AIDS Society

Volume:

Volume 20, Number 1

Publisher:

, Pages 21848-21848

Type of Work:

Article | Final Publisher PDF

Abstract:

INTRODUCTION: The transition from paediatric to adult HIV care is a particularly high-risk time for disengagement among young adults; however, empirical data are lacking. METHODS: We reviewed medical records of 72 youth seen in both the paediatric and the adult clinics of the Grady Infectious Disease Program in Atlanta, Georgia, USA, from 2004 to 2014. We abstracted clinical data on linkage, retention and virologic suppression from the last two years in the paediatric clinic through the first two years in the adult clinic. RESULTS: Of patients with at least one visit scheduled in adult clinic, 97% were eventually seen by an adult provider (median time between last paediatric and first adult clinic visit = 10 months, interquartile range 2-18 months). Half of the patients were enrolled in paediatric care immediately prior to transition, while the other half experienced a gap in paediatric care and re-enrolled in the clinic as adults. A total of 89% of patients were retained (at least two visits at least three months apart) in the first year and 56% in the second year after transition. Patients who were seen in adult clinic within three months of their last paediatric visit were more likely to be virologically suppressed after transition than those who took longer (Relative risk (RR): 1.76; 95% confidence interval (CI): 1.07-2.9; p = 0.03). Patients with virologic suppression (HIV-1 RNA below the level of detection of the assay) at the last paediatric visit were also more likely to be suppressed at the most recent adult visit (RR: 2.3; 95% CI: 1.34-3.9; p = 0.002). CONCLUSIONS: Retention rates once in adult care, though high initially, declined significantly by the second year after transition. Pre-transition viral suppression and shorter linkage time between paediatric and adult clinic were associated with better outcomes post-transition. Optimizing transition will require intensive transition support for patients who are not virologically controlled, as well as support for youth beyond the first year in the adult setting.

Copyright information:

© 2017 Hussen S A et al; licensee International AIDS Society

This is an Open Access work distributed under the terms of the Creative Commons Attribution 3.0 Unported License (http://creativecommons.org/licenses/by/3.0/).

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