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Author Notes:

Correspondence should be addressed to Andr´e P. Kengne, apkengne@yahoo.com

Subjects:

Estimation of absolute cardiovascular risk in individuals with diabetes mellitus: rationale and approaches.

Tools:

Journal Title:

ISRN Cardiology

Volume:

Volume 2011

Publisher:

, Pages 242656-242656

Type of Work:

Article | Final Publisher PDF

Abstract:

Purpose. To examine the usefulness of cardiovascular risk estimation models in people with diabetes. Methods. Review of published studies that compare the discriminative power of major cardiovascular risk factors single or in combination in individuals with and without diabetes, for major cardiovascular outcomes. Results. In individuals with and without diabetes, major risk factors affect cardiovascular risk similarly, with no evidence of any significant interaction. Accounting for diabetes-specific parameters, cardiopreventative therapies can significantly improve risk estimation in diabetes. General and diabetes-specific cardiovascular risk models have a useful discriminative power, but tend to overestimate risk in individuals with diabetes. Their impact on care delivery, adherence to therapies, and patients' outcome remain poorly understood. Conclusions. The high-risk status conferred by diabetes does not preclude the estimation of absolute cardiovascular risk estimation using global risk tools in individuals with diabetes, as this is useful for the initiation and intensification of preventive measures.

Copyright information:

© 2011 Justin B. Echouffo-Tcheugui et al.

This is an Open Access work distributed under the terms of the Creative Commons Attribution 3.0 Unported License (http://creativecommons.org/licenses/by/3.0/).

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