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Author Notes:

Correspondence should be addressed to Andrew Reisner, Andrew.Reisner@choa.org

The authors wish to acknowledge the administrative and technical support of the various personnel and institutions involved in publishing this paper.

The authors report no conflict of interest concerning the materials or methods used in this study or the findings specified in this paper.


Research Funding:

No financial assistance was granted during the production of this paper.

Intracranial metastatic neuroblastoma treated with gamma knife stereotactic radiosurgery: report of two novel cases.


Journal Title:

Case Reports in Neurological Medicine


Volume 2012


, Pages 690548-690548

Type of Work:

Article | Final Publisher PDF


Intracranial metastasis of neuroblastoma (IMN) is associated with poor survival. No curative therapy for the treatment of IMN currently exists. Unfractionated radiotherapy may be beneficial in the treatment of IMN given the known radiosensitivity of neuroblastoma as well as its proclivity to metastasize as discrete lesions. We present two patients with IMN treated with Gamma Knife stereotactic radiosurgery (SRS). Single-fraction radiotherapy yielded temporary reduction of tumor burden and stability of disease in both patients. SRS may be a useful palliative tool in the treatment of IMN and expands the overall treatment options for this disease.

Copyright information:

© 2012 Nathan C. Rowland et al.

This is an Open Access work distributed under the terms of the Creative Commons Attribution 3.0 Unported License (http://creativecommons.org/licenses/by/3.0/).

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