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Author Notes:

Corresponding author: Department of Neurosurgery, Emory University School of Medicine, 1365 Clifton Road, Northeast, Suite 6200, Atlanta, GA 30322. rgross@emory.edu

R.E. Gross served as a consultant to Visualase and Medtronic and received compensation for these services.

The terms of this arrangement have been reviewed and approved by Emory University in accordance with its conflict of interest policies.

Subjects:

Research Funding:

Funding was provided to Emory University by way of a clinical study agreement from Visualase, which developed products related to the research described in this article.

D.L. Drane receives funding from the NIH/NINDS (K02 NS070960), which provides support for his work.

Keywords:

  • Science & Technology
  • Life Sciences & Biomedicine
  • Clinical Neurology
  • Surgery
  • Neurosciences & Neurology
  • Mesial temporal lobe epilepsy
  • Mesial temporal sclerosis
  • Laser
  • Anterior temporal lobectomy
  • Selective amygdalohippocampectomy
  • Ablation
  • Neuropsychology
  • Memory
  • QUALITY-OF-LIFE
  • REFRACTORY EPILEPSY
  • SURGERY
  • RECOGNITION
  • STIMULATION
  • DEFICITS
  • OUTCOMES
  • TRIAL
  • TIME
  • MRI

The Role of Stereotactic Laser Amygdalohippocampotomy in Mesial Temporal Lobe Epilepsy

Tools:

Journal Title:

Neurosurgery Clinics of North America

Volume:

Volume 27, Number 1

Publisher:

, Pages 37-+

Type of Work:

Article | Post-print: After Peer Review

Abstract:

Stereotactic laser amygdalohippocampotomy (SLAH) uses laser interstitial thermal therapy guided by magnetic resonance thermography. This novel intervention can achieve seizure freedom while minimizing collateral damage compared to traditional open surgery, in patients with mesial temporal lobe epilepsy. An algorithm is presented to guide treatment decisions for initial and repeat procedures in patients with and without mesial temporal sclerosis. SLAH may improve access by medication-refractory patients to effective surgical treatments and thereby decrease medical complications, increase productivity, and minimize socioeconomic consequences in patients with chronic epilepsy.

Copyright information:

© 2016 Elsevier Inc.

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