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Author Notes:

REPRINT REQUESTS AND CORRESPONDENCE: Dr. Leslee J. Shaw, Emory Clinical Cardiovascular Research Institute, Emory University School of Medicine, Room 529, 1462 Clifton Road NE, Atlanta, Georgia 30324. Ishaw3@emory.edu

Dr. Raman has received research support from Siemens Healthcare; and is a co-inventor and founding member of EXCMR.

Dr. Bucciarelli-Ducci is a consultant for Circle Cardiovascular Imaging.

Dr. Ferdinand is a consultant for Amgen, Sanofi, Boehringer Ingelheim, and Eli Lilly; and has received research support from Boehringer Ingelheim.

All other authors have reported that they have no relationships relevant to the contents of this paper to disclose.

Jonathon Leipsic, MD, served as Guest Editor for this paper.

Subjects:

Research Funding:

Dr. Min is a consultant for HeartFlow; is on the Scientific Advisory Board of Arineta; has ownership of MDDX and Autoplak; has a research agreement with GE Healthcare; and is the recipient of grants NIH/NIHLBI R01HL111141, NIH/NIHLBI R01HL115150, NIH/NIHLBI R01HL118019, NIH/NIHLBI U01HL105907, and NPRP09-370-3-089.

Dr. Bairey Merz has received grant support from Gilead, Practive Point, and Medscape.

Dr. Pepine received grant UL1TR001427 from the National Center for Advancing Translational Sciences.

Dr. Shaw has received the Dean’s Distinguished Faculty Award and the Albert E. Levy Scientific Research Award from Emory University; and has received grant support from the Woodruff Foundation and the Antinori Foundation, and grants NIH-NHLBI R01HL118019-02, R01HL111150, and 1U01HL10556-01; and is a past president of the American Society of Nuclear Cardiology and President-Elect of the Society of Cardiovascular Computed Tomography.

Keywords:

  • Science & Technology
  • Life Sciences & Biomedicine
  • Cardiac & Cardiovascular Systems
  • Radiology, Nuclear Medicine & Medical Imaging
  • Cardiovascular System & Cardiology
  • imaging
  • prognosis
  • sex
  • women
  • CORONARY-ARTERY-DISEASE
  • CARDIOVASCULAR MAGNETIC-RESONANCE
  • COMPUTED-TOMOGRAPHY ANGIOGRAPHY
  • SYNDROME EVALUATION WISE
  • MYOCARDIAL-PERFUSION SPECT
  • INTERNATIONAL MULTICENTER CONFIRM
  • INTRAVASCULAR ULTRASOUND ANALYSIS
  • POSITRON-EMISSION-TOMOGRAPHY
  • OPTICAL COHERENCE TOMOGRAPHY
  • GENDER-RELATED DIFFERENCES

Noninvasive Imaging to Evaluate Women With Stable Ischemic Heart Disease

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Journal Title:

JACC: Cardiovascular Imaging

Volume:

Volume 9, Number 4

Publisher:

, Pages 421-435

Type of Work:

Article | Post-print: After Peer Review

Abstract:

Declines in cardiovascular deaths have been dramatic for men but occur significantly less in women. Among patients with symptomatic ischemic heart disease (IHD), women experience relatively worse outcomes compared with their male counterparts. Evidence to date has failed to adequately explore unique female imaging targets and their correlative signs and symptoms of IHD as major determinants of IHD risk. We highlight sex-specific anatomic and functional differences in contemporary imaging and introduce imaging approaches that leverage refined targets that may improve IHD risk prediction and identify potential therapeutic strategies for symptomatic women.

Copyright information:

© 2016 American College of Cardiology Foundation.

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