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Author Notes:

Email: spqrytdal@cdc.gov

Conceived and designed the experiments: DR MCRB MBG STB CLO MH CG UP JV BL.

Performed the experiments: SHS.

Analyzed the data: SG SHS.

Contributed reagents/materials/analysis tools: DR SHS MCRB MBG STB CLO MH CG JV BL.

Wrote the paper: SG BL.

We kindly acknowledge Azra Shahidi, Fletcher Fernau, Bailey Fay, E. Clayton Carruth, Rondeen Mindley, Brenda Clark, Blanca Vargas, and Chu-Tang (Sean) Yee for assisting with laboratory specimen and clinical data collection for this study.

The findings and conclusions in this report are those of the authors and do not necessarily represent the official position of the Centers for Disease Control and Prevention or Department of Veterans Affairs.

Competing Interests: The authors have declared that no competing interests exist.

Research Funding:

Funding provided by Centers for Disease Control and Prevention.

The funders participated in the study design, data analysis, decision to publish, and preparation of the manuscript.


  • Science & Technology
  • Multidisciplinary Sciences
  • Science & Technology - Other Topics

Incidence of Medically-Attended Norovirus-Associated Acute Gastroenteritis in Four Veteran's Affairs Medical Center Populations in the United States, 2011-2012

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Journal Title:



Volume 10, Number 5


, Pages e0126733-e0126733

Type of Work:

Article | Final Publisher PDF


An estimated 179 million acute gastroenteritis (AGE) illnesses occur annually in the United States. The role of noroviruses in hospital-related AGE has not been well-documented in the U. S. We estimated the population incidence of community- acquired outpatient and inpatient norovirus AGE encounters, as well as hospital-acquired inpatient norovirus AGE among inpatients at four Veterans Affairs (VA) Medical Centers (VAMCs). Fifty (4%) of 1,160 stool specimens collected ≤7 days from symptom onset tested positive for norovirus. During a one year period, the estimated incidence of outpatient, community- and hospital-acquired inpatient norovirus AGE was 188 cases, 11 cases, and 54 cases/ 100,000 patients, respectively. This study demonstrates the incidence of outpatient and community- and hospital-acquired inpatient norovirus AGE among the VA population seeking care at these four VAMCs.

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This is an Open Access work distributed under the terms of the Creative Commons Universal : Public Domain Dedication License (http://creativecommons.org/publicdomain/zero/1.0/).

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