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Correspondence: shankar@ucsd.edu (S.S.), bpulend@emory.edu (B.P.).
H.I.N., S.S.D., M.K., N.R., D.F., A.K.M., G.-M.L., R.A., M.J.M., and B.B.B. collected, processed, and prepared samples and assisted with the analyses.
H.I.N. and T.H. performed most of the microarray analyses.
E.K.L. performed the DAMIP model analyses.
T.H. performed the neural network predictive analyses.
S.S.D. and M.K. performed the FACS analyses.
R.G. and S.S.-O. performed the deconvolution analyses.
S.S. and B.P. supervised the analyses.
M.G. and S.G. assisted with analysis of microarray data.
B.P., R.A., N.R., and M.J.M. conceived the study and designed the experiments.
H.I.N., T.H., S.S., and B.P. wrote the paper.
We are grateful to Mary Bower, Srilatha Edugupanti, and the Hope Clinic Staff who assisted with the clinical work. We also thank Emory Immunology/Flow Cytometry Core for technical assistance.
The GEO accession numbers for the microarray data reported in this paper are GSE74817 (influenza seasons 2009–2012) and GSE29619 (influenza seasons 2007–2009).
This work was supported by NIH grants U19AI090023 (B.P.), U19AI057266 (R.A. and B.P.), HHSN272201400004C (B.P.), U54AI057157 (B.P.), R37AI48638 (B.P.), and R37DK057665 (B.P.) and NSF Grant STC-0939370 (S.S.).
H.I.N. receives a CNPq (Brazilian Research Council) research fellowship.
© 2015 Elsevier Inc.