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Author Notes:
Address for correspondence: Dr. Michael Mazzeffi, University of Maryland School of Medicine, 22 South Greene Street S11C00, Baltimore, MD 21201, USA. E-mail: mmazzeffi@anes.umm.edu
Conflict of Interest: None declared.
Subjects:
Keywords:
- cardiac surgery
- dissociative anesthesia
- intensive care
- ketamine
- anesthesiology
Ketamine in adult cardiac surgery and the cardiac surgery Intensive Care Unit: An evidence-based clinical review
Abstract:
Ketamine is a unique anesthetic drug that provides analgesia, hypnosis, and amnesia with minimal respiratory and cardiovascular depression. Because of its sympathomimetic properties it would seem to be an excellent choice for patients with depressed ventricular function in cardiac surgery. However, its use has not gained widespread acceptance in adult cardiac surgery patients, perhaps due to its perceived negative psychotropic effects. Despite this limitation, it is receiving renewed interest in the United States as a sedative and analgesic drug for critically ill-patients. In this manuscript, the authors provide an evidence-based clinical review of ketamine use in cardiac surgery patients for intensive care physicians, cardio-thoracic anesthesiologists, and cardio-thoracic surgeons. All MEDLINE indexed clinical trials performed during the last 20 years in adult cardiac surgery patients were included in the review.
Copyright information:
© 2015 Annals of Cardiac Anaesthesia
This is an Open Access work distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 3.0 Unported License (http://creativecommons.org/licenses/by-nc-sa/3.0/).
