About this item:

672 Views | 711 Downloads

Author Notes:

Corresponding author at: School of Public Health, Emory University, 1518 Clifton Rd., Atlanta, GA 30322, USA. Tel.: +1 404 969 5395; fax: +1 404 500 4283. Email: rwaford@emory.edu

The NAPLS principal investigators were responsible for the design of the whole study or aspects of it and the supervision of all aspects of data collection.

Dr. Rachel Waford took the lead on writing the manuscript with help in writing from all authors.

All authors contributed to and approved the final manuscript.

J Stowkowy, T Raedler, L McGregor, D Marulanda, L Legere, L Liu, C Marshall, E Falukozi, E Fitton, and K Smith (University of Calgary); T Alderman, K Shafer, I Domingues, and A Hurria, H Mirzakhanian (UCSD); B Walsh, J Saksa, N Santamauro, A Carlson, J Kenney, and B Roman (Yale University); K Woodberry, AJ Giuliano, W Stone, JM Rodenhiser, L Tucker, R Serur, G Min, and R Szent-Imrey (Beth Israel Deaconess Medical Center/Harvard); P Bachman, J Zinberg, S DeSilva, A Andaya, and S Uguryan (UCLA). J Brasfield (Emory University); A Pelletier, K Lansing, H Mates, J Nieri, B Landaas, K Graham, E Rothman, J Hurta, and Y Sierra (University of North Carolina) and A Auther, R Carrion, M McLaughlin, and R Olsen (Zucker Hillside Hospital) are gratefully acknowledged.

The NIMH had no further role in the study design; in the collection, analysis and interpretation of data; in the writing of the report; and in the decision to submit the paper for publication.

The views expressed are those of the authors and do not necessarily reflect the official views of the National Institute of Mental Health, the National Institutes of Health, or any other branch of the US Department of Health and Human Services.

Authors report no biomedical financial interests or potential conflicts of interest.

Subjects:

Research Funding:

This study was supported by the National Institute of Mental Health (grant U01MH081988 to Dr. Walker; grant U01MH081984 to Dr. Addington; grant P50 MH066286 and Staglin Music Festival for Mental Health to Dr. Bearden; grants U01MH081928; P50 MH080272; Commonwealth of Massachusetts SCDMH82101008006 to Dr. Seidman; grants R01MH60720, U01MH082022 and K24MH76191 to Dr. Cadenhead; grant MH081902 to Dr. Cannon; grant U01MH082004-01A1 to Dr. Perkins; grant U01MH082022 to Dr. Woods; and grant UO1 MH081857-05 to Dr. Cornblatt).

For more details on each author's funding please see original paper

Keywords:

  • Science & Technology
  • Life Sciences & Biomedicine
  • Psychiatry
  • Prodrome
  • Psychosis
  • Sex
  • Education
  • Early identification
  • 1ST EPISODE PSYCHOSIS
  • HIGH-RISK
  • GENDER-DIFFERENCES
  • BASE-LINE
  • FOLLOW-UP
  • 1ST-EPISODE SCHIZOPHRENIA
  • PRODROMAL SYMPTOMS
  • SEX-DIFFERENCES
  • YOUNG-PEOPLE
  • AGE

Demographic correlates of attenuated positive psychotic symptoms

Show all authors Show less authors

Tools:

Journal Title:

Schizophrenia Research

Volume:

Volume 166, Number 1-3

Publisher:

, Pages 31-36

Type of Work:

Article | Post-print: After Peer Review

Abstract:

It is now well established that the utilization of standardized clinical criteria can enhance prediction of psychosis. These criteria are primarily concerned with the presence and severity of attenuated positive symptoms. Because these symptom criteria are used to derive algorithms for designating clinical high risk (CHR) status and for maximizing prediction of psychosis risk, it is important to know whether the symptom ratings vary as a function of demographic factors that have previously been linked with symptoms in diagnosed psychotic patients. Using a sample of 356 CHR individuals from the NAPLS-II multi-site study, we examined the relation of three sex, age, and educational level, with the severity of attenuated positive symptom scores from the Scale of Prodromal Symptoms (SOPS). Demographic factors accounted for little of the variance in symptom ratings (5-6%). Older CHR individuals manifested more severe suspiciousness, and female CHR participants reported more unusual perceptual experiences than male participants. Contrary to prediction, higher educational level was associated with more severe ratings of unusual thought content, but less severe perceptual abnormalities. Overall, sex, age and education were modestly related to unusual thought content and perceptual abnormalities, only, suggesting minimal implication for designating CHR status and predicting psychosis-risk.

Copyright information:

© 2015 Elsevier B.V. All rights reserved.

Export to EndNote