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Address correspondence to: Jeff M. Sands, Emory University School of Medicine, Renal Division, 101 Woodruff Circle, WMB 338, Atlanta, Georgia 30322 USA. Phone: 404.727.2525; Email: jeff.sands@emory.edu
OE planned and executed experiments, collected and analyzed data, and wrote the manuscript.
JDK planned experiments, prepared samples, analyzed data, and edited the manuscript.
LML prepared samples and collected data.
HR prepared samples and collected data.
JMS planned the project, analyzed data, and edited the manuscript.
The authors have declared that no conflict of interest exists.
This work was supported by NIH grant R01-DK41707 and by an Otsuka Investigator-Sponsored Study (20135297).
Tolvaptan was a gift from Otsuka.
The V2R KO mice were a gift from Jurgen Wess, NIH.
© 2016, American Society for Clinical Investigation