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Author Notes:
Authors to whom correspondence should be addressed; E-Mails: jjacob3@emory.edu (J.J.); sgeorge@rgcb.res.in (S.G.); Tel.: +1-404-727-7919 (J.J.); +91-471-252-9520 (S.G.).
Author Contributions: Vineeth T.V. Kumar, David Holthausen, Joshy Jacob and Sanil George wrote the paper.
The authors declare no conflict of interest.
Subjects:
Research Funding:
Vineeth T.V. Kumar and Sanil George are thankful to Kerala State Council for Science, Technology and Environment (KSCSTE), Govt. of Kerala, India for financial assistance. Grant No: (No.006/SRSLS/2011/CSTE).
Keywords:
- Anti-microbial peptides
- Asian frog
- Host defense peptides
- Multi-drug resistance
Host Defense Peptides from Asian Frogs as Potential Clinical Therapies.
Abstract:
Host defense peptides (HDPs) are currently major focal points of medical research as infectious microbes are gaining resistance to existing drugs. They are effective against multi-drug resistant pathogens due to their unique primary target, biological membranes, and their peculiar mode of action. Even though HDPs from 60 Asian frog species belonging to 15 genera have been characterized, research into these peptides is at a very early stage. The purpose of this review is to showcase the status of peptide research in Asia. Here we provide a summary of HDPs from Asian frogs.
Copyright information:
© 2015 by the authors; licensee MDPI, Basel, Switzerland.
This is an Open Access work distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/).
