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Author Notes:

Correspondence: Sheila T. Angeles-Han, MD, MSc, Division of Pediatric Rheumatology, Emory University, 2015 Uppergate Drive, Atlanta, GA 30307; Phone: 404-778-2400; Fax: 404-727-3757; Email: sangele@emory.edu

or Steven Yeh, MD, Section of Vitreoretinal Surgery, Department of Ophthalmology, Emory University, 1365B Clifton Rd. NE, Atlanta, GA 30322; Phone: 404-778-5070; Fax: 404-778-4380; Email: steven.yeh@emory.edu

or Neal Palejwala, MD, Section of Vitreoretinal Surgery, Department of Ophthalmology, Emory University, 1365B Clifton Rd. NE, Atlanta, GA 30322; Phone: 404-778-4530; Fax: 404-778-4380; Email: neal.palejwala@emory.edu

Disclosures: Neal V. Palejwala declares that he has no conflict of interest.

Sheila T. Angeles-Han declares that she has no conflict of interest.

This article does not contain any studies with human or animal subjects performed by any of the authors.

The content is solely the responsibility of the authors and does not necessarily represent the official views of the National Institutes of Health.


Research Funding:

Sheila T. Angeles-Han was supported by the National Eye Institute of the National Institutes of Health under award no. K23 EY021760.

Steven Yeh has received research support via an unrestricted grant from Research to Prevent Blindness (Emory Eye Center), the Knights Templar Educational Foundation of Georgia, and NEI Core Grant for Vision Research (P30 EY 006360); He has also received grant support from Abbott Laboratories and Novartis.


  • Pediatrics
  • Rheumatic diseases
  • Ophthalmology
  • Biologic
  • Juvenile idiopathic arthritis
  • Eye
  • Systemic lupus erythematosus
  • Behcet’s disease
  • Juvenile spondyloarthropathy
  • HLA-B27
  • Spondyloarthropathy
  • Uveitis
  • Childhood
  • Treatment

Current Perspectives on Ophthalmic Manifestations of Childhood Rheumatic Diseases


Journal Title:

Current Rheumatology Reports


Volume 15, Number 7


, Pages 341-341

Type of Work:

Article | Post-print: After Peer Review


Inflammatory eye diseases are an important manifestation of many pediatric rheumatologic conditions. Early screening and diagnosis are imperative as these illnesses can not only result in significant visual morbidity but also be an indicator of systemic inflammation. Time to presentation of ocular inflammation varies significantly and can range from many years prior to the onset of systemic symptoms to well after the diagnosis of the rheumatologic disorder. Due to this variability in presentation, careful monitoring by an ophthalmologist is vital to preventing ocular complications and preserving vision. Both local and systemic immunosuppressive medications have been effective in the management of ocular disease. In this review, we will focus on the known ophthalmologic manifestations of common pediatric rheumatologic diseases and discuss recent advances in therapeutic considerations for these conditions.

Copyright information:

© 2013, Springer Science+Business Media New York

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