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Author Notes:

Correspondence to: Dr. Xiaodong Zhang, 954 Gatewood Rd NE, Atlanta, GA 30329, USA, Telephone: 1-404-712-9874, Fax: 1-404-712-9917, xzhang8@emory.edu


Research Funding:

This project was supported in part by the National Center for Research Resources (P51RR000165) of NIH and by the Office of Research Infrastructure Programs (OD P51OD011132).


  • MRSI
  • spectral curve fitting
  • multiscale analysis
  • in vivo MR spectroscopy
  • chemical shift imaging (CSI)
  • automatic phase correction

Peak-specific phase correction for automated spectrum processing of in vivo magnetic resonance spectroscopic imaging by using the multiscale approach


Journal Title:

Chinese Journal of Magnetic Resonance


Volume 31, Number 1


, Pages 32-39

Type of Work:

Article | Post-print: After Peer Review


Automatic metabolite quantification with curve fitting is essential in analyzing large amount of in vivo magnetic resonance spectroscopic imaging (MRSI) data. However, such data analysis is usually hindered by distorted metabolite peaks and baselines normally seen in in vivo MRS. In the present study, a multiscale approach was utilized for peak-specific automatic phase correction in multi-slice MRSI data of human brain. The results suggest that this novel approach can improve the robustness and efficiency of metabolite quantification and facilitate automatic analysis of multi-slice in vivo MRSI data in human brain.

Copyright information:

© Chinese Journal of Magnetic Resonance

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