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Author Notes:

Corresponding author. Tel.: +1 404 727 5970; fax: +1 404 712 2974. dpjones@emory.edu

Subject:

Research Funding:

This work was supported by NIH grants ES009047, HL113451, AG38746 and ES019116.

Keywords:

  • Oxidative stress
  • Redox signaling
  • Life cycle
  • Environmental exposures
  • Personalized medicine

Redox biology: Interface of the exposome with the proteome, epigenome and genome

Tools:

Journal Title:

Redox Biology

Volume:

Volume 2

Publisher:

, Pages 358-360

Type of Work:

Article | Final Publisher PDF

Abstract:

The exposome is the cumulative measure of environmental influences and associated biological responses throughout lifespan, including exposures from the environment, diet, behavior and endogenous processes. Much of the direct interaction of an individual's exposome involves redox biology as the body responds to environmental, dietary and behavioral risk factors of disease. The present commentary addresses this critical interface and the need for redox biologists to lead development of concepts and strategies to sequence the exposome.

Copyright information:

© 2014 The Authors

This is an Open Access work distributed under the terms of the Creative Commons Attribution-NonCommerical-NoDerivs 3.0 Unported License (http://creativecommons.org/licenses/by-nc-nd/3.0/).

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