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Author Notes:

Correspondence: Guillermo E. Umpierrez, M.D. Associate Professor of Medicine Associate Director, General Clinical Research Center Emory University School of Medicine Director, Diabetes and Endocrinology Section Grady Health System 49 Jesse Hill Jr Dr Atlanta, GA 30303; Tel: 404- 778 1665, Fax: 404- 778 1661, Email: geumpie@emory.edu

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Research Funding:

Dr Umpierrez is supported by research grants from the American Diabetes Association (7-03-CR-35), American Heart Association (0555306B), and National Institutes of Health: R03 DK073190-01 and General Clinical Research Center Grant M01 RR-00039.

Prevalence and Clinical Outcome of Inpatient Hyperglycemia in a Community Pediatric Hospital

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Journal Title:

Journal of Hospital Medicine

Volume:

Volume 3, Number 3

Publisher:

, Pages 212-217

Type of Work:

Article | Post-print: After Peer Review

Abstract:

Background Inpatient hyperglycemia in adult patients with and without a history of diabetes is a predictor of poor clinical outcome. No previous studies; however, have examined the association of hyperglycemia and clinical outcome in children admitted to a community pediatric hospital. Methods Retrospective observational cohort of pediatric patients admitted to a community children's hospital, from January 2004 to August 2004. Medical records of 903 consecutive children admitted to critical and non-critical care areas were reviewed. Of them, 342 patients (38%) had no blood glucose measurements during the hospital stay. In the remaining patients, we determined the prevalence of hyperglycemia and examined the association of hyperglycemia and clinical outcome. Results A total of 406 patients (75%) had an admission blood glucose ≤ 120 mg/dl [(mean 98 ± 1 mg/dl (± SEM)], 103 children (19%) had an admission blood glucose level between 121–179 mg/dl (mean 143 ± 2 mg/dl), and 32 patients (5.9%) had a blood glucose level ≥ 180 mg/dl (mean 260 ± 18 mg/dl). Seventeen patients (13%) had a known history of diabetes prior to admission. Children with hyperglycemia were more likely to be admitted to the ICU (p<0.001) and had a longer length of ICU stay (p<0.001), but admission hyperglycemia was not associated with longer hospital stay or higher hospital mortality. Summary Hyperglycemia is present in one-fourth of children admitted to the hospital, most of them without a history of diabetes prior to admission. Hyperglycemia was associated with a greater need for ICU care and longer ICU stay but not with increased in-hospital mortality.

Copyright information:

© 2008 Society of Hospital Medicine

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