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Author Notes:

bfei@emory.edu; phone 1 (404) 712-5649; fax 1(404)712-5689; www.feilab.org

We thank Dr. Aaron Fenster at Robart Research Institute of The University of Western Ontario for providing the ultrasound images.

Subjects:

Research Funding:

NIH grant R01CA156775 (PI: Fei)

Coulter Translational Research Grant (PIs: Fei and Hu)

Georgia Cancer Coalition Distinguished Clinicians and Scientists Award (PI: Fei)

Emory Molecular and Translational Imaging Center (NIH P50CA128301)

Atlanta Clinical and Translational Science Institute (ACTSI) that is supported by the PHS Grant UL1 RR025008 from the Clinical and Translational Science Award program

Keywords:

  • Prostate segmentation
  • Ultrasound image segmentation
  • Wavelet based segmentation
  • Support Vector Machines
  • kernel support vector machine
  • transrectal ultrasound image

3D Segmentation of Prostate Ultrasound images Using Wavelet Transform

Tools:

Journal Title:

Proceedings of SPIE

Volume:

Volume 7962

Publisher:

, Pages 79622K-79622K

Type of Work:

Article | Post-print: After Peer Review

Abstract:

The current definitive diagnosis of prostate cancer is transrectal ultrasound (TRUS) guided biopsy. However, the current procedure is limited by using 2D biopsy tools to target 3D biopsy locations. This paper presents a new method for automatic segmentation of the prostate in three-dimensional transrectal ultrasound images, by extracting texture features and by statistically matching geometrical shape of the prostate. A set of Wavelet-based support vector machines (W-SVMs) are located and trained at different regions of the prostate surface. The WSVMs capture texture priors of ultrasound images for classification of the prostate and non-prostate tissues in different zones around the prostate boundary. In the segmentation procedure, these W-SVMs are trained in three sagittal, coronal, and transverse planes. The pre-trained W-SVMs are employed to tentatively label each voxel around the surface of the model as a prostate or non-prostate voxel by the texture matching. The labeled voxels in three planes after post-processing is overlaid on a prostate probability model. The probability prostate model is created using 10 segmented prostate data. Consequently, each voxel has four labels: sagittal, coronal, and transverse planes and one probability label. By defining a weight function for each labeling in each region, each voxel is labeled as a prostate or non-prostate voxel. Experimental results by using real patient data show the good performance of the proposed model in segmenting the prostate from ultrasound images.

Copyright information:

© 2011 SPIE

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