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Author Notes:

Correspondence and requests for reprints should be addressed to Matthew J. Strickland, Ph.D., M.P.H., Department of Environmental and Occupational Health, 1518 Clifton Road NE, Atlanta, GA 30322. E-mail: mjstric@emory.edu

Subjects:

Research Funding:

Supported by grants from National Institute of Environmental Health Sciences (R01ES012967), Environmental Protection Agency (STAR R82921301), and the Electric Power Research Institute (EP-P27723/C13172).

Keywords:

  • ambient particulate matter
  • asthma
  • minors
  • ozone

Short-term Associations between Ambient Air Pollutants and Pediatric Asthma Emergency Department Visits

Tools:

Journal Title:

American Journal of Respiratory and Critical Care Medicine

Volume:

Volume 182, Number 3

Publisher:

, Pages 307-316

Type of Work:

Article | Post-print: After Peer Review

Abstract:

Rationale: Certain outdoor air pollutants cause asthma exacerbations in children. To advance understanding of these relationships, further characterization of the dose–response and pollutant lag effects are needed, as are investigations of pollutant species beyond the commonly measured criteria pollutants. Objectives: Investigate short-term associations between ambient air pollutant concentrations and emergency department visits for pediatric asthma. Methods: Daily counts of emergency department visits for asthma or wheeze among children aged 5 to 17 years were collected from 41 Metropolitan Atlanta hospitals during 1993–2004 (n = 91,386 visits). Ambient concentrations of gaseous pollutants and speciated particulate matter were available from stationary monitors during this time period. Rate ratios for the warm season (May to October) and cold season (November to April) were estimated using Poisson generalized linear models in the framework of a case-crossover analysis. Measurements and Main Results: Both ozone and primary pollutants from traffic sources were associated with emergency department visits for asthma or wheeze; evidence for independent effects of ozone and primary pollutants from traffic sources were observed in multipollutant models. These associations tended to be of the highest magnitude for concentrations on the day of the emergency department visit and were present at relatively low ambient concentrations. Conclusions: Even at relatively low ambient concentrations, ozone and primary pollutants from traffic sources independently contributed to the burden of emergency department visits for pediatric asthma.

Copyright information:

© 2010, American Thoracic Society

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