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Corresponding author: Dr. Stephen F. Traynelis, Department of Pharmacology, Emory University, Rollins Research Center Rm 5025, 1510 Clifton Rd, Atlanta, GA 30322, USA. Tel: 404-727-0357. strayne@emory.edu
Author contributions: S.G., S.A.S., S.F.T. and D.W. planned the experiments.
S.G., S.A.S. and J.Z. performed the research.
S.G. and S.A.S. analyzed the data.
S.G., S.A.S., D.W. and S.F.T. discussed the results.
All authors wrote the manuscript.
We thank Dr. Ethel Garnier-Amblard for synthesizing preladenant.
The authors have no conflict of interest to declare.
Funding was provided by NINDS NRSA (F31NS076215, S.G.), NIH Pharmacological Sciences institutional training grant (T32GM008602, S.G.), and a pilot grant from the Emory University Alzheimer's Disease Research Center (NIHP50 AG025688, S.F.T.).
© 2016 IBRO. Published by Elsevier Ltd. All rights reserved.