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Author Notes:

Email Address: Andrey V Olypher: aolypher@biology.emory.edu; Ronald L Calabrese: ronald.calabrese@emory.edu


Variations of neuronal parameters that do not change network output


Journal Title:

BMC Neuroscience


Volume 8, Number Suppl 2


, Pages P165-P165

Type of Work:

Article | Final Publisher PDF


Neuronal network modeling and experiments indicate that the same physiologically relevant patterns of the network activity can be observed for quite different sets of neuronal parameters. These findings imply that parameters, each of which affects network functionality, co-vary in real networks; i.e. the variations of these parameters must be concordant. Finding such concordant variations can advance our understanding on how the properties of individual neurons determine network functionality. In particular, they may explain variability of neuronal parameters observed in living systems, and show possible paths for homeostatic regulation.

Copyright information:

© 2007 Olypher and Calabrese

This is an Open Access article distributed under the terms of the Creative Commons Attribution 2.0 Generic License ( http://creativecommons.org/licenses/by/2.0/), which permits distribution, public display, and publicly performance, distribution of derivative works, making multiple copies, provided the original work is properly cited. This license requires copyright and license notices be kept intact, credit be given to copyright holder and/or author.

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