Subra Kugathasan MD

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Works 1-10 of 66

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Article

Mucosal Expression of Type 2 and Type 17 Immune Response Genes Distinguishes Ulcerative Colitis From Colon-Only Crohn's Disease in Treatment-Naive Pediatric Patients

by Michael J. Rosen; Rebekah Karns; Jefferson E. Vallance; Ramona Bezold; Amanda Waddell; Margaret H. Collins; Yael Haberman; Phillip Minar; Robert N. Baldassano; Jeffrey S. Hyams; Susan S. Baker; Richard Kellermayer; Joshua D. Noe; Anne M. Griffiths; Joel R. Rosh; Wallace V. Crandall; Melvin B. Heyman; David R. Mack; Michael D. Kappelman; James Markowitz; Dedrick E. Moulton; Neal S. Leleiko; Thomas D. Walters; Subra Kugathasan; Keith T. Wilson; Simon P. Hogan; Lee A. Denson

2017

Article

NOX1 loss-of-function genetic variants in patients with inflammatory bowel disease

by T. Schwerd; R.V. Bryant; S. Pandey; M. Capitani; L. Meran; J.-B. Cazier; J. Jung; K. Mondal; M. Parkes; C.G. Mathew; K. Fiedler; D.J. McCarthy; P.B. Sullivan; A. Rodrigues; S.P.L. Travis; C. Moore; J. Sambrook; W.H. Ouwehand; D.J. Roberts; J. Danesh; R.K. Russell; D.C. Wilson; J.R. Kelsen; R. Cornall; L.A. Denson; Subra Kugathasan; U.G. Knaus; E. Goncalves Serra; C.A. Anderson; R.H. Duerr; D.P.B. McGovern; J. Cho; F. Powrie; V.S.W. Li; A.M. Muise; H.H. Uhlig

2018

Article

Impaired antibacterial autophagy links granulomatous intestinal inflammation in Niemann-Pick disease type C1 and XIAP deficiency with NOD2 variants in Crohn's disease

by Tobias Schwerd; Sumeet Pandey; Huei-Ting Yang; Katrin Bagola; Elisabeth Jameson; Jonathan Jung; Robin H Lachmann; Neil Shah; Smita Y Patel; Claire Booth; Heiko Runz; Gesche Dueker; Ruth Bettels; Marianne Rohrbach; Subramaniam Kugathasan; Helen Chapel; Satish Keshav; Abdul Elkadri; Nick Platt; Alexio M Muise; Sibylle Koletzko; Ramnik J Xavier; Thorsten Marquardt; Fiona Powrie; James E Wraith; Mads Gyrd-Hansen; Frances M Platt; Holm H Uhlig

2017

Article

Machine learning identifies novel blood protein predictors of penetrating and stricturing complications in newly diagnosed paediatric Crohn's disease

by Ryan C. Ungaro; Liangyuan Hu; Jiayi Ji; Shikha Nayar; Subramaniam Kugathasan; Lee A. Denson; Jeffrey Hyams; Marla C. Dubinsky; Bruce E. Sands; Judy H. Cho

2020

Article

Complexity of Secretory Chemokines in Human Intestinal Organoid Cultures Ex Vivo.

by Subramaniam Kugathasan; Jason Matthews; C Cottle; M Anbazhagan; A Lipat; M Patel; AP Porter; K Hogan; D Rajan; R Chinnadurai

2022

Article

PTSD is associated with increased DNA methylation across regions of HLA-DPB1 and SPATC1L

by Alicia Smith; Charles Gillespie; Vasiliki Michopoulos; Suresh Venkateswaran; Adriana Lori; Kerry Ressler; Aliza Wingo; Subramaniam Kugathasan; Tanja Jovanovic; Abigail Lott; S Katrinli; Y Zheng; A Gautam; R Hammamieh; R Yang; V Kilaru; R Hinrichs; A Powers; EJ Wolf; RE McGlinchey; WP Milberg; MW Miller; M Jett; MW Logue

2021

Article

Deconvolution of monocyte responses in inflammatory bowel disease reveals an IL-1 cytokine network that regulates IL-23 in genetic and acquired IL-10 resistance

by Subramaniam Kugathasan; D Aschenbrenner; M Quaranta; S Banerjee; N Ilott; J Jansen; B Steere; Y-H Chen; S Ho; K Cox; CV Arancibia-Carcamo; M Coles; E Gaffney; SP Travis; L Denson; J Schmitz; F Powrie; SN Sansom; HH Uhlig

2021

Article

Host-microbe interactions have shaped the genetic architecture of inflammatory bowel disease

by Luke Jostins; Stephan Ripke; Rinse K Weersma; Richard H Duerr; Dermot P McGovern; Ken Y Hui; James C Lee; L Philip Schumm; Yashoda Sharma; Carl A Anderson; Jonah Essers; Mitja Mitrovic; Kaida Ning; Isabelle Cleynen; Emilie Theatre; Sarah L Spain; Soumya Raychaudhuri; Philippe Goyette; Zhi Wei; Clara Abraham; Subramaniam Kugathasan

2012

Article

Challenges in IBD Research: Update on Progress and Prioritization of the CCFA's Research Agenda

by Lee A. Denson; Millie D. Long; Dermot P. B. McGovern; Subramaniam Kugathasan; Gary D. Wu; Vincent B. Young; Theresa T. Pizarro; Edwin F. de Zoeten; Thaddeus S. Stappenbeck; Scott E. Plevy; Clara Abraham; Asma Nusrat; Christian Jobin; Declan F. McCole; Corey A. Siegel; Peter D. R. Higgins; Hans H. Herfarth; Jeffrey Hyams; William J. Sandborn; Edward V. Loftus,Jr.; Michael D. Kappelman; James D. Lewis; Charles Parkos; R. Balfour Sartor

2013