This report describes the case of a previously healthy 30-year-old woman who presented with uncontrolled hypertension and renal failure. This case emphasizes the importance of considering renal artery disease. The differential diagnosis for renal artery stenosis is discussed, and the diagnosis and management of Takayasu's arteritis in this patient are highlighted. (Level of Difficulty: Beginner.)
Identifying idiopathic inflammatory myopathies (IIM), including dermatomyositis (DM), clinically amyopathic dermatomyositis (CADM), and polymyositis (PM), remains clinically challenging. Testing for myositis-associated (MAA) and myositis-specific (MSA) autoantibodies is an increasingly important tool to aid in IIM diagnosis and phenotyping. Data from research cohorts suggest MSA may be found in over 50% of DM and PM patients1,2. Commercial myositis autoantibody panel testing is now widely available, but studies evaluating performance of these assays is limited.