Mehul Suthar

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Works 1-10 of 65

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Article

SARS-CoV-2 RBD trimer protein adjuvanted with Alum-3M-052 protects from SARS-CoV-2 infection and immune pathology in the lung

by Rama Amara; Mehul Suthar; Lilin Lai; Thomas Vanderford; Narayanaiah Cheedarla; Sanjeev Gumber; Sailaja Gangadhara; Nanda Kishore Routhu; VS Bollimpelli; VV Edara; A Sahoo; A Shiferaw; TM Styles; K Floyd; S Fischinger; C Atyeo; SA Shin; S Kirejczyk; KH Dinnon; P-Y Shi; VD Menachery; M Tomai; CB Fox; G Alter; L Gralinski

2021

Article

Caspase-4/11 exacerbates disease severity in SARS–CoV-2 infection by promoting inflammation and immunothrombosis

by Mehul Suthar; Amy Girard; Jacob Kohlmeier; MM Eltobgy; A Zani; AD Kenney; S Estfanous; E Kim; A Badr; C Carafice; K Daily; O Whitham; M Pietrzak; A Webb; J Kawahara; AC Eddy; P Denz; M Lu; KC Mahesh; ME Peeples; J Li; J Zhu; J Que; R Robinson; OR Mejia; RE Rayner; L Hall-Stoodley; S Seveau; MA Gavrilin; X Zhang; J Thomas; E Oltz; A Tedeschi; FH Robledo-Avila; S Partida-Sanchez; EA Hemann; E Abdelrazik; A Forero; SM Nimjee; PN Boyaka; E Cormet-Boyaka; JS Yount; AO Amer

2022

Article

Contrasting behavior between the three human monocyte subsets in dengue pathophysiology

by Mehul Suthar; Anmol Chandele; Murali Kaja; Rafi Ahmed; Evan Anderson; D Maheshwari; K Saini; P Singh; M Singla; K Nayak; C Aggarwal; YM Chawla; P Bajpai; M Kaur; S Gunisetty; CS Eberhardt; R Nyodu; K Moore; GR Medigeshi; R Lodha; SK Kabra; K Murali-Krishna

2022

Article

A yeast expressed RBD-based SARS-CoV-2 vaccine formulated with 3M-052-alum adjuvant promotes protective efficacy in non-human primates

by Kirk Easley; Mehul Suthar; Sudhir Kasturi; Joyce Cohen; Sherrie Jean; Jennifer Wood; Fawn Connor-Stroud; Thomas Vanderford; Rachelle Stammen; Sanjeev Gumber; Mirko Paiardini; Susan Pereira Ribeiro; Muhammad Latif; Rafick-Pierre Sekaly; M Pino; T Abid; SP Ribeiro; VV Edara; K Floyd; JC Smith; G Pacheco-Sanchez; D Dutta; S Wang; S Kirejczyk; J Pollet; W-H Chen; J Wei; B Zhan; J Lee; Z Liu; U Strych; N Shenvi; D Weiskopf; A Sette; J Pollara; D Mielke; H Gao; N Eisel; CC LaBranche; X Shen; G Ferrari; GD Tomaras; DC Montefiori; MA Tomai; CB Fox; PA Kozlowski; PJ Hotez; ME Bottazzi

2021

Article

Booster of mRNA-1273 Strengthens SARS-CoV-2 Omicron Neutralization.

by Mehul Suthar; Lilin Lai; NA Doria-Rose; X Shen; SD Schmidt; S O'Dell; C McDanal; W Feng; J Tong; A Eaton; M Maglinao; H Tang; KE Manning; V-V Edara; M Ellis; K Moore; K Floyd; SL Foster; RL Atmar; KE Lyke; T Zhou; L Wang; Y Zhang; MR Gaudinski; WP Black; I Gordon; M Guech; JE Ledgerwood; JN Misasi; A Widge; PC Roberts; J Beigel; B Korber; R Pajon; JR Mascola; DC Montefiori

2021

Article

Longitudinal analysis shows durable and broad immune memory after SARS-CoV-2 infection with persisting antibody responses and memory B and T cells

by Aneesh Mehta; Srilatha Edupuganti; Nadine Rouphael; David Stephens; Rafi Ahmed; Mehul Suthar; Carl Davis; Evan Anderson; James O'Keefe; Jens Wrammert; Veronika Zarnitsyna; Rustom Antia; KW Cohen; SL Linderman; Z Moodie; J Czartoski; L Lai; G Mantus; C Norwood; LE Nyhoff; VV Edara; K Floyd; SC De Rosa; R Whaley; SN Patel; B Prigmore; MP Lemos; S Furth; MP Gharpure; S Gunisetty; MS Sulthar; MJ McElrath

2021

Article

SARS-CoV-2 spike-protein D614G mutation increases virion spike density and infectivity

by Lizhou Zhang; Cody B. Jackson; Huihui Mou; Amrita Ojha; Haiyong Peng; Brian D. Quinlan; Erumbi S. Rangarajan; Andi Pan; Abigail Vanderheiden; Mehul Suthar; Wenming Li; Tina Izard; Christoph Rader; Michael Farzan; Hyeryun Choe

2020

Article

Durability of mRNA-1273-induced antibodies against SARS-CoV-2 variants.

by Nadine Rouphael; Mehul Suthar; Lilin Lai; Evan Anderson; Paulina Rebolledo; Christina Rostad; A Pegu; S O'Connell; SD Schmidt; S O'Dell; CA Talana; J Albert; H Bennett; KS Corbett; B Flach; L Jackson; B Leav; JE Ledgerwood; CJ Luke; M Makowski; PC Roberts; M Roederer; W Shi; L Wang; AT Widge; ES Yang; mRNA-1273 Study Group; JH Beigel; BS Graham; JR Mascola; A McDermott; NA Doria-Rose

2021

Article

Mouse Adapted SARS-CoV-2 protects animals from lethal SARS-CoV challenge.

by Mehul Suthar; A Muruato; MN Vu; BA Johnson; ME Davis-Gardner; A Vanderheiden; K Lokugmage; C Schindewolf; PA Crocquet-Valdes; RM Langsjoen; JA Plante; KS Plante; SC Weaver; K Debbink; AL Routh; D Walker; X Xie; P-Y Shi; X Xie; VD Menachery

2021