Jeong Hong

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Works 1-10 of 11

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Article

An Ancient CFTR Ortholog Informs Molecular Evolution in ABC Transporters

by Guiying Cui; Jeong Hong; Yu-Wen Chung-Davidson; Daniel Infield; Xin Xu; Jindong Li; Luba Simhaev; Netaly Khazanov; Brandon Stauffer; Barry Imhoff; Kirsten Cottrill; J. Edwin Blalock; Weiming Li; Hanoch Senderowitz; Eric Sorscher; Nael McCarty; Amit Gaggar

2019

Article

The CFTR P67L variant reveals a key role for N-terminal lasso helices in channel folding, maturation, and pharmacologic rescue

by Carleen Mae Sabusap; Disha Joshi; Luba Simhaev; Kathryn Oliver; Hanoch Senderowitz; Marcel van Willigen; Ineke Brakkman; Andras Rab; Eric Sorscher; Jeong Hong

2021

Article

Channel Gating Regulation by the Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) First Cytosolic Loop

by Annette Ehrhardt; Wook Chung; Louise C. Pyle; Wei Wang; Krzysztof Nowotarski; Cory M. Mulvihill; Mohabir Rannjeesingh; Jeong Hong; Sadanandan E. Velu; Hal A. Lewis; Shane Atwell; Steve Aller; Christine E. Bear; Gergely L. Lukacs; Kevin L. Kirk; Eric Sorscher

2016

Article

Residual function of cystic fibrosis mutants predicts response to small molecule CFTR modulators.

by Sangwoo T. Han; Andras Rab; Matthew J. Pellicore; Emily F. Davis; Allison F. McCague; Taylor A. Evans; Anya T. Joynt; Zhongzhou Lu; Zhiwei Cai; Karen S. Raraigh; Jeong Hong; David N. Sheppard; Eric J. Sorscher; Garry R. Cutting

2018

Article

Making precision medicine personal for cystic fibrosis

by Candela Manfredi; Janice M. Tindall; Jeong Hong; Eric Sorscher

2019

Article

Slowing ribosome velocity restores folding and function of mutant CFTR

by Kathryn E. Oliver; Robert Rauscher; Marjolein Mijnders; Wei Wang; Matthew J. Wolpert; Jessica Maya; Carleen M. Sabusap; Robert A. Kesterson; Kevin L. Kirk; Andras Rab; Ineke Braakman; Jeong Hong; John L. Hartman, IV; Zoya Ignatova; Eric Sorscher

2019

Article

Non-obstructive vas deferens and epididymis loss in cystic fibrosis rats

by Z.E. Plyler; S.E. Birket; B.D. Schultz; Jeong Hong; S.M. Rowe; C.F. Petty; M.R. Crowley; D.K. Grossman; T.R. Schoeb; Eric Sorscher

2019

Article

Analysis of cystic fibrosis-associated P67L CFTR illustrates barriers to personalized therapeutics for orphan diseases

by Carleen M. Sabusap; Wei Wang; Carmel M. McNicholas; Wook Joon Chung; Lianwu Fu; Hui Wen; Marina Mazur; Kevin L. Kirk; James F. Collawn; Jeong Hong; Eric Sorscher

2016