Jeong Hong

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Works 1-10 of 16

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Article

Engineered tRNAs suppress nonsense mutations in cells and in vivo

by Suki Albers; Elizabeth C Allen; Nikhil Bharti; Marcos Davyt; Disha Joshi; Carlos G Perez-Garcia; Leonardo Santos; Rajesh Mukthavaram; Miguel Angel Delgado-Toscano; Brandon Molina; Kristen Kuakini; Maher Alayyoubi; Kyoung-Joo Jenny Park; Grishma Acharya; Jose A Gonzalez; Amit Sagi; Susan E Birket; Guillermo J Tearney; Steven M Rowe; Candela Manfredi; Jeong Hong; Kiyoshi Tachikawa; Priya Karmali; Daiki Matsuda; Eric Sorscher; Pad Chivukula; Zoya Ignatova

2023

Article

Stability Prediction for Mutations in the Cytosolic Domains of Cystic Fibrosis Transmembrane Conductance Regulator

by Malkeet S Bahia; Netaly Khazanov; Qingxian Zhou; Zhengrong Yang; Chi Wang; Jeong Hong; Andras Rab; Eric Sorscher; Christie G Brouillette; John F Hunt; Hanoch Senderowitz

2021

Article

Elexacaftor/VX-445-mediated CFTR interactome remodeling reveals differential correction driven by mutation-specific translational dynamics.

by Minsoo Kim; Eli Fritz McDonald; Carleen MP Sabusap; Bibek Timalsina; Disha Joshi; Jeong S Hong; Jeong Hong; Andras Rab; Eric Sorscher; Lars Plate

2023

Article

Increasing the Endoplasmic Reticulum Pool of the F508del Allele of the Cystic Fibrosis Transmembrane Conductance Regulator Leads to Greater Folding Correction by Small Molecule Therapeutics

by Wook Chung; Jennifer L. Goeckeler-Fried; Viktoria Havasi; Annette Chiang; Steven M. Rowe; Zackery E. Plyler; Jeong Hong; Marina Mazur; Gary A Piazza; Adam B. Keeton; E. Lucile White; Lynn Rasmussen; Allan M. Weissman; R. Aldrin Denny; Jeffrey L. Brodsky; Eric Sorscher

2016

Article

Antisense oligonucleotide-based drug development for Cystic Fibrosis patients carrying the 3849+10 kb C-to-T splicing mutation

by Yifat S Oren; Michal Irony-Tur Sinai; Anita Golec; Ofra Barchad-Avitzur; Venkateshwar Mutyam; Yao Li; Jeong Hong; Efrat Ozeri-Galai; Aurélie Hatton; Chen Leibson; Liran Carmel; Joel Reiter; Eric Sorscher; Steve D Wilton; Eitan Kerem; Steven M Rowe; Isabelle Sermet-Gaudelus; Batsheva Kerem

2021

Article

A small molecule that induces translational readthrough of CFTR nonsense mutations by eRF1 depletion

by Jyoti Sharma; Ming Du; Eric Wong; Venkateshwar Mutyam; Yao Li; Jianguo Chen; Jamie Wangen; Kari Thrasher; Lianwu Fu; Ning Peng; Liping Tang; Kaimao Liu; Bini Mathew; Robert J. Bostwick; Corinne E. Augelli-Szafran; Hermann Bihler; Feng Liang; Jerome Mahiou; Josef Saltz; Andras Rab; Jeong Hong; Eric Sorscher; Eric M. Mendenhall; Candice J. Coppola; Kim M. Keeling; Rachel Green; Martin Mense; Mark J. Suto; Steven M. Rowe; David M. Bedwell

2021

Article

The use of Trichomonas vaginalis purine nucleoside phosphorylase to activate fludarabine in the treatment of solid tumors

by William B Parker; Paula W Allan; William R Waud; Jeong Hong; Melissa Gilbert-Ross; BR Achyut; Disha Joshi; Turang Behbahani; Regina Rab; SE Ealick; Eric Sorscher

2020

Article

An Ancient CFTR Ortholog Informs Molecular Evolution in ABC Transporters

by Guiying Cui; Jeong Hong; Yu-Wen Chung-Davidson; Daniel Infield; Xin Xu; Jindong Li; Luba Simhaev; Netaly Khazanov; Brandon Stauffer; Barry Imhoff; Kirsten Cottrill; J. Edwin Blalock; Weiming Li; Hanoch Senderowitz; Eric Sorscher; Nael McCarty; Amit Gaggar

2019

Article

The CFTR P67L variant reveals a key role for N-terminal lasso helices in channel folding, maturation, and pharmacologic rescue

by Carleen Mae Sabusap; Disha Joshi; Luba Simhaev; Kathryn Oliver; Hanoch Senderowitz; Marcel van Willigen; Ineke Brakkman; Andras Rab; Eric Sorscher; Jeong Hong

2021

Article

Channel Gating Regulation by the Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) First Cytosolic Loop

by Annette Ehrhardt; Wook Chung; Louise C. Pyle; Wei Wang; Krzysztof Nowotarski; Cory M. Mulvihill; Mohabir Rannjeesingh; Jeong Hong; Sadanandan E. Velu; Hal A. Lewis; Shane Atwell; Steve Aller; Christine E. Bear; Gergely L. Lukacs; Kevin L. Kirk; Eric Sorscher

2016