Hongjie Yuan

Contact Information:

Phone: 404-712-1375

Email: hyuan@emory.edu

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School/Division:

Asst Professor

SOM: Pharmacology: Admin

School Of Medicine

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Works 1-10 of 19

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Article

Mechanism for Noncompetitive Inhibition by Novel GluN2C/D N-Methyl-d-aspartate Receptor Subunit-Selective Modulators

by Timothy M. Acker; Hongjie Yuan; Kasper B. Hansen; Katie M. Vance; Kevin K. Ogden; Henrik S. Jensen; Pieter B. Burger; Praseeda Mullasseril; James P Snyder; Dennis C Liotta; Stephen Traynelis

2011

Article

Synthesis, structural activity-relationships, and biological evaluation of novel amide-based allosteric binding site antagonists in NR1A/NR2B N-methyl-D-aspartate receptors

by Cara A. Mosley; Scott J. Myers; Ernest E. Murray; Rose Santangelo; Yesim A. Tahirovic; Natalie Kurtkaya; Praseeda Mullasseril; Hongjie Yuan; Polina Lyuboslavsky; Phuong Le; Lawrence Wilson; Manuel Yepes; Raymond J Dingledine; Stephen F. Traynelis; Dennis C Liotta

2009

Article

Molecular Mechanism of Disease-Associated Mutations in the Pre-M1 Helix of NMDA Receptors and Potential Rescue Pharmacology.

by Kevin K. Ogden; Wenjuan Chen; Sharon A. Swanger; Miranda J. McDaniel; Linlin Z. Fan; Chun Hu; Anel Tankovic; Hirofumi Kusumoto; Gabrielle J. Kosobucki; Anthony J. Schulien; Zhuocheng Su; Joseph Pecha; Subhrajit Bhattacharya; Slavé Petrovski; Adam E. Cohen; Elias Aizenman; Stephen Traynelis; Hongjie Yuan

2017

Article

Implementation of a Fluorescence-Based Screening Assay Identifies Histamine H3 Receptor Antagonists Clobenpropit and Iodophenpropit as Subunit-Selective N-Methyl-d-Aspartate Receptor Antagonists

by Kasper B. Hansen; Praseeda Mullasseril; Sara Dawit; Natalie L. Kurtkaya; Hongjie Yuan; Katie M. Vance; Anna G. Orr; Trine Kvist; Kevin K. Ogden; Phuong Le; Kimberly M. Vellano; Iestyn Lewis; Serdar Kurtkaya; Yuhong Du; Min Qui; T J Murphy; James P Snyder; Hans Bräuner-Osborne; Stephen Traynelis

2010

Article

Human GRIN2B variants in neurodevelopmental disorders

by Chun Hu; Wenjuan Chen; Scott J. Myers; Hongjie Yuan; Stephen Traynelis

2016

Article

GRIN2B encephalopathy: novel findings on phenotype, variant clustering, functional consequences and treatment aspects

by Konrad Platzer; Hongjie Yuan; Hannah Schuetz; Alexander Winschel; Wenjuan Chen; Chun Hu; Hirofumi Kusumoto; Henrike O. Heyne; Katherine L. Helbig; Sha Tang; Marcia C. Willing; Brad T. Tinkle; Darius J. Adams; Christel Depienne; Boris Keren; Cyril Mignot; Elrik Frengen; Petter Stromme; Saskia Biskup; Dennis Doecker; Tim M. Strom; Heather C. Mefford; Candace T. Myers; Alison M. Muir; Amy LaCroix; Lynette Sadleir; Ingrid E. Scheffer; Eva Brilstra; Mieke M. van Haelst; Jasper J. van der Smagt; Levinus A. Bok; Rikke S. Moller; Uffe B. Jensen; John J. Millichap; Anne T. Berg; Ethan M. Goldberg; Isabelle De Bie; Stephanie Fox; Philippe Major; Julie R. Jones; Elaine H. Zackai; Rami Abou Jamra; Arndt Rolfs; Richard J. Leventer; John A. Lawson; Tony Roscioli; Floor E. Jansen; Emmanuelle Ranza; Christian M. Korff; Anna-Elina Lehesjoki; Carolina Courage; Tarja Linnankivi; Douglas R. Smith; Christine Stanley; Mark Mintz; Dianalee McKnight; Amy Decker; Wen-Hann Tan; Mark A. Tarnopolsky; Lauren I. Brady; Markus Wolff; Lutz Dondit; Helio F. Pedro; Srah E. Parisotto; Kelly L. Jones; Anup D. Patel; David N. Franz; Rena Vanzo; Elysa Marco; Judith D. Ranells; Nataliya Di Donato; William B. Dobyns; Bodo Laube; Stephen Traynelis; Johannes R. Lemke

2017

Article

Functional analysis of a de novo GRIN2A missense mutation associated with early-onset epileptic encephalopathy

by Hongjie Yuan; Kasper B. Hansen; Jing Zhang; Tyler Mark Pierson; Thomas C. Markello; Karin V. Fuentes Fajardo; Conisha M. Holloman; Gretchen Golas; David R. Adams; Cornelius F. Boerkoel; William A. Gahl; Stephen Traynelis

2014

Article

GRIN2A mutation and early-onset epileptic encephalopathy: personalized therapy with memantine

by Tyler Mark Pierson; Hongjie Yuan; Eric D. Marsh; Karin Fuentes-Fajardo; David R. Adams; Thomas Markello; Gretchen Golas; Dimitre R. Simeonov; Conisha Holloman; Anel Tankovic; Manish M. Karamchandani; John M. Schreiber; James C. Mullikin; Cynthia J. Tifft; Camilo Toro; Cornelius F. Boerkoel; Stephen Traynelis; William A. Gahl

2014

Article

A Rare Variant Identified Within the GluN2B C-Terminus in a Patient with Autism Affects NMDA Receptor Surface Expression and Spine Density

by Shuxi Liu; Liang Zhou; Hongjie Yuan; Marta Vieira; Antonio Sanz-Clemente; John D. Badger; Wei Lu; Stephen Traynelis; Katherine W. Roche

2017

Article

GRIN1 mutation associated with intellectual disability alters NMDA receptor trafficking and function

by Wenjuan Chen; Christine Shieh; Sharon Swanger; Anel Tankovic; Margaret Au; Marianne McGuire; Michele Tagliati; John M. Graham; Suneeta Madan-Khetarpal; Stephen Traynelis; Hongjie Yuan; Tyler Mark Pierson

2017