Hui Mao PhD

Affiliations:

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External Links (e.g. Departmental web site):

Degrees Held:

  • PhD, Georgia State University, 1994
  • MSc, Nanjing University, 1988

Biography/Description of Research:

Dr. Mao is widely recognized for his expertise in a range of scientific fields, including chemistry, biochemistry, biomaterials, neurosciences, cancer, medical imaging technology and nanomedicine. Dr. Mao directs Precision and Quantitative Imaging and Image-Guided Technology Program and Laboratory of Functional and Molecular Imaging and Nanomedicine (LFMI&N), which focuses on developing and utilizing cutting-edge functional and molecular imaging technologies to advance early detection and molecular characterizations of diseases for precision medicine. Dr. Mao is a Distinguished Investigator of the Academy for Radiology & Biomedical Imaging Research, Fellow of American Institute for Medical and Biological Engineering (AIMBE) and Fellow of International Society of Magnetic Resonance in Medicine (ISMRM). Regarded as one of the leading experts in the field of molecular imaging, he regularly serves on expert review panels and was a Charter Member and past chair of the NIH Study Section for Clinical Molecular Imaging and Probe Development. Dr. Mao is currently associate editor of Radiology: Imaging Cancer.

The research projects in Dr. Mao's laboratory are focusing on developing and utilizing imaging technologies, especially magnetic resonance methods, to address biological questions and solve medical problems in the areas of cancer and degenerative diseases with strong emphases on translational research and clinical applications. His research program, which has been supported continuously by NIH grants in past 20 years, has made and continues to make contributions in biomedical discoveries and engineering advances in the following areas: 1) developing biomarker targeted MRI contrast agents for MRI-based molecular and cellular imaging; 2) developing NMR/MRS based metabolomics to profile cell or tissue metabolites in vivo and ex vivo to investigate the potential metabolite markers for improving the specificity of cancer detection and for early diagnosis of neurodegenerative diseases; 3) developing nanomaterial and nanotechnology for image-guided drug delivery and interventions and in vitro diagnostics; 4) developing clinical applications of advanced MRI technologies for imaging and study of brain functions, brain disorders and diseases, as well as image-guided treatment; 5) developing machine- and deep-learning based automatic image analysis and diagnostics;

Works 1-10 of 130

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Article

Trans-vaccenic acid reprograms CD8+ T cells and anti-tumour immunity

by Hao Fan; Siyuan Xia; Junhong Xiang; Yuancheng Li; Matthew O. Ross; Seon Ah Lim; Fan Yang; Jiayi Tu; Lishi Xie; Urszula Dougherty; Freya Q. Zhang; Zhong Zheng; Rukang Zhang; Rong Wu; Lei Dong; Rui Su; Xiufen Chen; Thomas Althaus; Peter A. Riedell; Patrick B. Jonker; Alexander Muir; Gregory Lesinski; Sarwish Rafiq; Madhav V. Dhodapkar; Wendy Stock; Olatoyosi Odenike; Anand A. Patel; Joseph Opferman; Takemasa Tsuji; Junko Matsuzaki; Hardik Shah; Brandon Faubert; Shannon E. Elf; Brian Layden; B. Marc Bissonnette; Yu-Ying He; Justin Kline; Hui Mao; Kunle Odunsi; Xue Gao; Hongbo Chi; Chuan He; Jing Chen

2023

Article

Mutant and Wild-Type Isocitrate Dehydrogenase 1 Share Enhancing Mechanisms Involving Distinct Tyrosine Kinase Cascades in Cancer

by Dong Chen; Siyuan Xia; Mei Wang; Ruiting Lin; Yuancheng Li; Hui Mao; Mike Aguiar; Christopher A. Famulare; Alan H. Shih; Cameron W. Brennan; Xue Gao; Yaozhu Pan; Shuangping Liu; Jun Fan; Lingtao Jin; Lina Song; An Zhou; Joydeep Mukherjee; Russell O. Pieper; Ashutosh Mishra; Junmin Peng; Martha Arellano; William Blum; Sagar Lonial; Titus J. Boggon; Ross L. Levine; Jing Chen

2019

Article

A two years longitudinal study of a transgenic Huntington disease monkey

by Anthony Chan; Yan Xu; Jie Jiang; Tayeb Rahim; Dongming Zhao; Jannet Kocerha; Tim Chi; Sean Moran; Heidi Engelhardt; Katherine Larkin; Adam Neumann; Haiying Cheng; Chunxia Li; Katie Nelson; Heather Banta; Stuart M Zola; Francois Villinger; Jin Jing Yang; Claudia M Testa; Hui Mao; Xiaodong Zhang; Jocelyne Bachevalier

2014

Article

Discovery of a dual inhibitor of NQO1 and GSTP1 for treating glioblastoma

by Kecheng Lei; Xiaoxia Gu; Alvaro G. Alvarado; Yuhong Du; Shilin Luo; Eun Hee Ahn; Seong Kang; Bing Ji; Xia Liu; Hui Mao; Haian Fu; Harley I. Kornblum; Lingjing Jin; Hua Li; Keqiang Ye

2020