Eric Sorscher MD

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Works 1-10 of 33

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Article

Engineered tRNAs suppress nonsense mutations in cells and in vivo

by Suki Albers; Elizabeth C Allen; Nikhil Bharti; Marcos Davyt; Disha Joshi; Carlos G Perez-Garcia; Leonardo Santos; Rajesh Mukthavaram; Miguel Angel Delgado-Toscano; Brandon Molina; Kristen Kuakini; Maher Alayyoubi; Kyoung-Joo Jenny Park; Grishma Acharya; Jose A Gonzalez; Amit Sagi; Susan E Birket; Guillermo J Tearney; Steven M Rowe; Candela Manfredi; Jeong Hong; Kiyoshi Tachikawa; Priya Karmali; Daiki Matsuda; Eric Sorscher; Pad Chivukula; Zoya Ignatova

2023

Article

Stability Prediction for Mutations in the Cytosolic Domains of Cystic Fibrosis Transmembrane Conductance Regulator

by Malkeet S Bahia; Netaly Khazanov; Qingxian Zhou; Zhengrong Yang; Chi Wang; Jeong Hong; Andras Rab; Eric Sorscher; Christie G Brouillette; John F Hunt; Hanoch Senderowitz

2021

Article

Evaluating antitumor activity of Escherichia coli purine nucleoside phosphorylase against head and neck patient-derived xenografts

by Regina Rab; Annette Ehrhardt; Bhagelu R Achyut; Disha Joshi; Melissa Gilbert-Ross; Chunzi Huang; Katharine Floyd; Anton V Borovjagin; William B Parker; Eric Sorscher; Jeong S Hong

2023

Article

Elexacaftor/VX-445-mediated CFTR interactome remodeling reveals differential correction driven by mutation-specific translational dynamics.

by Minsoo Kim; Eli Fritz McDonald; Carleen MP Sabusap; Bibek Timalsina; Disha Joshi; Jeong S Hong; Jeong Hong; Andras Rab; Eric Sorscher; Lars Plate

2023

Article

SNP Formation Bias in the Murine Genome Provides Evidence for Parallel Evolution.

by Zackery E. Plyler; Aubrey E. Hill; Christopher W. McAtee; Xiangqin Cui; Leah A. Moseley; Eric Sorscher

2015

Article

Improved correction of F508del-CFTR biogenesis with a folding facilitator and an inhibitor of protein ubiquitination

by Jennifer L Goeckeler-Fried; Rajiah A Denny; Disha Joshi; Clare Hill; Mads B Larsen; Annette N Chiang; Raymond A Frizzell; Peter Wipf; Eric Sorscher; Jeffrey L Brodsky

2021

Article

Increasing the Endoplasmic Reticulum Pool of the F508del Allele of the Cystic Fibrosis Transmembrane Conductance Regulator Leads to Greater Folding Correction by Small Molecule Therapeutics

by Wook Chung; Jennifer L. Goeckeler-Fried; Viktoria Havasi; Annette Chiang; Steven M. Rowe; Zackery E. Plyler; Jeong Hong; Marina Mazur; Gary A Piazza; Adam B. Keeton; E. Lucile White; Lynn Rasmussen; Allan M. Weissman; R. Aldrin Denny; Jeffrey L. Brodsky; Eric Sorscher

2016

Article

Antisense oligonucleotide-based drug development for Cystic Fibrosis patients carrying the 3849+10 kb C-to-T splicing mutation

by Yifat S Oren; Michal Irony-Tur Sinai; Anita Golec; Ofra Barchad-Avitzur; Venkateshwar Mutyam; Yao Li; Jeong Hong; Efrat Ozeri-Galai; Aurélie Hatton; Chen Leibson; Liran Carmel; Joel Reiter; Eric Sorscher; Steve D Wilton; Eitan Kerem; Steven M Rowe; Isabelle Sermet-Gaudelus; Batsheva Kerem

2021

Article

Derivation of Airway Basal Stem Cells from Human Pluripotent Stem Cells

by Eric Sorscher; Finn J Hawkins; Shingo Suzuki; Mary Lou Beermann; Cristina Barillà; Ruobing Wang; Carlos Villacorta-Martin; Andrew Berical; JC Jean; Jake Le Suer; Taylor Matte; Chantelle Simone-Roach; Yang Tang; Thorsten M Schlaeger; Ana M Crane; Nadine Matthias; Sarah XL Huang; Scott H Randell; Joshua Wu; Jason R Spence; Gianni Carraro; Barry R Stripp; Andras Rab; Eric J Sorsher; Amjad Horani; Steven L Brody; Brian R Davis; Darrell N Kotton

2021

Article

Marine Natural Products as Leads against SARS-CoV-2 Infection

by Bhuwan K Chhetri; Philip Tedbury; Anne Marie Sweeney-Jones; Luke Mani; Katy Soapi; Candela Manfredi; Eric Sorscher; Stefan Sarafianos; Julia Kubanek

2022