Eric B Dammer Ph.D

Contact Information:

Phone: 404-712-8590

Email: edammer@emory.edu

View Emory directory entry

School/Division:

Scientist, Asc Bioinformatics

SOM: Core Labs

School Of Medicine

Other Affiliations:

  • School of Medicine: Core Labs

Degrees Held:

  • Ph.D, Applied Biology, Georgia Institute of Technology, 2008
  • B.A., Liberal Arts, Florida Gulf Coast Univ., 2003

Biography/Description of Research:

Dr. Dammer has established himself as a competent systems biology analyst with over 15 years of biochemistry, molecular biology, and mass spectrometry experience. Since 2015, he has engaged in building myriad networks of correlated abundance in proteomic and transcriptomic data to discover novel biology of disease, in particular Alzheimer's disease (AD). Since joining Emory in 2008, he has routinely performed mass spectrometry experiments, with biochemical validation and integration of analyses with external, multi-omic data including transcriptomics collected by microarray or RNA-Seq, and proteomics gathered in discovery mode by liquid chromatography-tandem mass spectrometry (Lc-MS/MS). A major research focus of Dr. Dammer’s is the analysis of differential expression and co-expression of proteins and protein post translational modifications (PTMs) in proteomic data sets, particularly those focused on mechanistic biomarkers of neurodegenerative disease such as Alzheimer’s disease (AD). Examples of his recent work on systems analysis of genomic, transcriptomic, and proteomic systems level analysis range from determination of cell type shifts in AD brain, to myelination changes in AD, to (co-)aggregation networks, to networks of pathophysiological marker panels in cerebrospinal fluid (CSF).

Works 1-10 of 43

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Article

Flow-cytometric microglial sorting coupled with quantitative proteomics identifies moesin as a highly-abundant microglial protein with relevance to Alzheimer's disease

by Sruti Rayaprolu; Tianwen Gao; Hailian Xiao; Supriya Ramesha; Laura D. Weinstock; Jheel Shah; Duc M. Duong; Eric Dammer; James A. Webster, Jr.; James Lah; Levi B. Wood; Ranjita Betarbet; Allan Levey; Nicholas Seyfried; Srikant Rangaraju

2020

Article

Polyubiquitin Linkage Profiles in Three Models of Proteolytic Stress Suggest the Etiology of Alzheimer Disease

by Eric B Dammer; Chan Hyun Na; Ping Xu; Nicholas Seyfried; Duc Duong; Dongmei Cheng; Marla Gearing; Howard D Rees III; James J Lah; Allan I Levey; John Rush; Junmin Peng

2011

Article

Tissue-Type Plasminogen Activator Regulates the Neuronal Uptake of Glucose in the Ischemic Brain

by Fang Wu; Jialing Wu; Andrew D. Nicholson; Ramiro Echeverry; Woldeab B. Haile; Marcela Catano; Jie An; Andrew K. Lee; Duc Duong; Eric B Dammer; Nicholas Seyfried; Frank Tong; John R Votaw; Robert Medcalf; Manuel Yepes

2012