Eric B Dammer Ph.D

School/Division:

Other Affiliations:

  • School of Medicine: Core Labs

Degrees Held:

  • Ph.D, Applied Biology, Georgia Institute of Technology, 2008
  • B.A., Liberal Arts, Florida Gulf Coast Univ., 2003

Biography/Description of Research:

Dr. Dammer has established himself as a competent systems biology analyst with over 15 years of biochemistry, molecular biology, and mass spectrometry experience. Since 2015, he has engaged in building myriad networks of correlated abundance in proteomic and transcriptomic data to discover novel biology of disease, in particular Alzheimer's disease (AD). Since joining Emory in 2008, he has routinely performed mass spectrometry experiments, with biochemical validation and integration of analyses with external, multi-omic data including transcriptomics collected by microarray or RNA-Seq, and proteomics gathered in discovery mode by liquid chromatography-tandem mass spectrometry (Lc-MS/MS). A major research focus of Dr. Dammer’s is the analysis of differential expression and co-expression of proteins and protein post translational modifications (PTMs) in proteomic data sets, particularly those focused on mechanistic biomarkers of neurodegenerative disease such as Alzheimer’s disease (AD). Examples of his recent work on systems analysis of genomic, transcriptomic, and proteomic systems level analysis range from determination of cell type shifts in AD brain, to myelination changes in AD, to (co-)aggregation networks, to networks of pathophysiological marker panels in cerebrospinal fluid (CSF).

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Article

Proteomics Links Ubiquitin Chain Topology Change to Transcription Factor Activation

by Yanchang Li; Eric Dammer; Yuan Gao; Qiuyan Lan; Mark A. Villamil; Duc M. Duong; Chengpu Zhang; Lingyan Ping; Linda Lauinger; Karin Flick; Zhongwei Xu; Wei Wei; Xiaohua Xing; Lei Chang; Jianping Jin; Xuechuan Hong; Yunping Zhu; Junzhu Wu; Zixin Deng; Fuchu He; Peter Kaiser; Ping Xu

2019

Article

Multivariant Transcriptome Analysis Identifies Modules and Hub Genes Associated with Poor Outcomes in Newly Diagnosed Multiple Myeloma Patients

by Lawrence Boise; Eric Dammer; Benjamin Barwick; OO Adebayo; CD Dill; AO Adebayo; SO Oseni; TL Griffen; AQ Ohandjo; F Yan; S Jain; R Singh; JW Lillard

2022

Article

Comparative proteomic analysis highlights metabolic dysfunction in alpha-synucleinopathy

by Souvarish Sarkar; Michael A. Murphy; Eric Dammer; Abby L. Olsen; Srikant Rangaraju; Ernest Fraenkel; Mel B. Feany

2020