Deborah DeRyckere PhD

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Works 1-10 of 15

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Article

Aberrant Mer receptor tyrosine kinase expression contributes to leukemogenesis in acute myeloid leukemia

by AB Lee-Sherick; KM Eisenman; S Sather; A McGranahan; PM Armistead; CS McGary; SA Hunsucker; J Schlegel; H Martinson; C Cannon; AK Keating; HS Earp; X Liang; Deborah DeRyckere; Doug Graham

2013

Article

Aberrant Mer receptor tyrosine kinase expression contributes to leukemogenesis in acute myeloid leukemia: CORRECTION

by AB Lee-Sherick; KM Eisenman; S Sather; A McGranahan; PM Armistead; CS McGary; SA Hunsucker; J Schlegel; H Martinson; C Cannon; AK Keating; HS Earp; X Liang; Deborah DeRyckere; Doug Graham

2016

Article

UNC2025, a MERTK Small-Molecule Inhibitor, Is Therapeutically Effective Alone and in Combination with Methotrexate in Leukemia Models

by Deborah DeRyckere; Alisa B. Lee-Sherick; Madeline G. Huey; Amanda A. Hill; Jeffrey W. Tyner; Kristen M. Jacobsen; Lauren S. Page; Gregory G. Kirkpatrick; Fatma Eryildiz; Stephanie A. Montgomery; Weihe Zhang; Xiaodong Wang; Stephen V. Frye; H. Shelton Earp; Doug Graham

2017

Article

Data-Driven Construction of Antitumor Agents with Controlled Polypharmacology

by Chenxiao Da; Dehui Zhang; Michael Stashko; Eleana Vasileiadi; Rebecca Parker; Katherine Minson; Madeline G. Huey; Justus M. Huelse; Debra Hunter; Thomas S. K. Gilbert; Jacqueline Norris-Drouin; Michael Miley; Laura E. Herring; Lee M. Graves; Deborah DeRyckere; H. Shelton Earp; Douglas Graham; Stephen V. Frye; Xiaodong Wang; Dmitri Kireev

2019

Article

MERTK inhibition alters the PD-1 axis and promotes anti-leukemia immunity.

by Alisa B. Lee-Sherick; Kristen M. Jacobsen; Curtis Henry; Madeline G. Huey; Rebecca E. Parker; Lauren S. Page; Amanda A. Hill; Xiaodong Wang; Stephen V. Frye; H. Shelton Earp; Craig T. Jordan; Deborah DeRyckere; Doug Graham

2018

Article

Discovery of Macrocyclic Pyrimidines as MerTK-Specific Inhibitors

by Dr. Andrew L. McIver; Dr. Weihe Zhang; Dr. Qingyang Liu; Dr. Xinpeng Jiang; Michael A. Stashko; James Nichols; Dr. Michael J Miley; Dr. Jacqueline Norris-Drouin; Dr. Mischa Machius; Deborah DeRyckere; Dr. Edgar Wood; Doug Graham; Prof. H Shelton Earp; Prof. Dmitri Kireev; Prof. Stephen V. Frye; Prof. Xiaodong Wang

2017

Article

Risk-associated alterations in marrow T cells in pediatric leukemia

by Jithendra Kini Bailur; Samual S. McCachren; Katherine Pendleton; Juan C. Vasquez; Hong Seo Lim; Alyssa Duffy; Deon B. Doxie; Akhilesh Kaushal; Connor Foster; Deborah DeRyckere; Sharon Castellino; Melissa Kemp; Peng Qiu; Madhav Dhodapkar; Kavita Dhodapkar

2020

Article

MERTK Inhibition Induces Polyploidy and Promotes Cell Death and Cellular Senescence in Glioblastoma Multiforme

by Alexandra Sufit; Alisa B. Lee-Sherick; Deborah DeRyckere; Manali Rupji; Bhakti Dwivedi; Marileila Varella-Garcia; Angela M. Pierce; Jeanne Kowalski; Xiaodong Wang; Stephen V. Frye; H. Shelton Earp; Amy K. Keating; Douglas Graham

2016