Trends in incidence of long-term-care facility onset Clostridium difficile infections in 10 US geographic locations during 2011-2015

• Type of Material: Article
• Authors: Alice Y. Guh, Centers for Disease Control and Prevention; Yi Mu, Centers for Disease Control and Prevention; James Baggs, Centers for Disease Control and Prevention; Lisa G. Winston, University of California San Francisco; Wendy Bamberg, Colorado Department of Public Health and Environment; Carol Lyons, Yale University; Monica Farley, Emory University; Lucy E. Wilson, Maryland Department of Health; Stacy M. Holzbauer, Centers for Disease Control and Prevention; Erin C. Phipps, University of New Mexico; Zintars G. Beldays, Oregon Health Authority; Marion A. Kainer, Tennessee Department of Health; Maria Karlsson, Centers for Disease Control and Prevention; Dale N. Gerding, Loyola University Chicago; Ghinwa Dumyati, University of Rochester
• Language: English
• Date: 2018-07-01
• Publisher: Elsevier: 12 months
• Publication Version: Author Accepted Manuscript (After Peer Review)
• Copyright Statement: © 2018 Elsevier Inc.
• License: Creative Commons Attribution-NonCommercial-NoDerivs 4.0 International
• Final Published Version (URL): http://dx.doi.org/10.1016/j.ajic.2017.11.026
• Title of Journal or Parent Work: American Journal of Infection Control
• ISSN: 0196-6553
• Volume: 46
• Issue: 7
• Start Page: 840
• End Page: 842
• Grant/Funding Information: Supported by the Emerging Infections Program and the National Center for Emerging and Zoonotic Infectious Diseases at the Centers for Disease Control and Prevention.
• Keywords: Infectious Diseases; NAP1/027; Fluoroquinolone; ENGLAND; Science & Technology; Public, Environmental & Occupational Health; Life Sciences & Biomedicine; EPIDEMIOLOGY
• Research Categories: Health Sciences, Public Health

Abstract

During 2011-2015, the adjusted long-term-care facility onset Clostridium difficile infection incidence rate in persons aged ≥65 years decreased annually by 17.45% (95% confidence interval, 14.53%-20.43%) across 10 US sites. A concomitant decline in inpatient fluoroquinolone use and the C difficile epidemic strain NAP1/027 among persons aged ≥65 years may have contributed to the decrease in long-term-care facility-onset C difficile infection incidence rate.