Comment on “Genomic epidemiology of superspreading events in Austria reveals mutational dynamics and transmission properties of SARS-CoV-2”

• Type of Material: Article
• Authors: Michael A Martin, Emory University; Katia Koelle, Emory University
• Language: English
• Date: 2021-10-27
• Publisher: American Association for the Advancement of Science.
• Publication Version: Author Accepted Manuscript (After Peer Review)
• Copyright Statement: © 2021 The Authors, some rights reserved; exclusive licensee American Association for the Advancement of Science. No claim to original U.S. Government Works.
• Final Published Version (URL): http://dx.doi.org/10.1126/scitranslmed.abh1803
• Title of Journal or Parent Work: Science Translational Medicine
• Volume: 13
• Issue: 617
• Start Page: eabh1803
• End Page: eabh1803
• Grant/Funding Information: The research reported in this technical comment was supported by National Institute of Allergy and Infectious Diseases Centers of Excellence for Influenza Research and Surveillance (CEIRS) grant HHSN272201400004C and by the US National Institutes of Health National Institute of General Medical Sciences grant 1R01 GM124280-03S1.
• Keywords: COVID-19; Mutation; Austria; Genomics; Humans; SARS-CoV-2

Abstract

A reanalysis of SARS-CoV-2 deep sequencing data from donor-recipient pairs indicates that transmission bottlenecks are very narrow (one to three virions).