ACR Appropriateness Criteria (R) Recurrent Hodgkin Lymphoma

• Type of Material: Article
• Authors: Karen M. Winkfield, Wake Forest University; Ranjana H. Advani, Stanford Cancer Center; Leslie K. Ballas, University of Southern California; Bouthaina S. Dabaja, University of Texas MD Anderson Cancer Center; Sughosh Dhakal, University of Rochester; Christopher Flowers, Emory University; Christopher R. Ha, University of Texas Health Science Center at San Antonio; Bradford S. Hoppe, University of Florida; David B. Mansur, Case Western Reserve University; Nancy P. Mendenhall, University of Florida; Monika L. Metzger, American Society of Clinical Oncology; John P. Plastaras, University of Pennsylvania Health System; Kenneth B. Roberts, Yale University; Ronald Shapiro, Indiana University; Sonali M. Smith, American Society of Clinical Oncology; Stephanie A. Terezakis, Johns Hopkins University; Anas Younes, American Society of Clinical Oncology; Louis S. Constine, University of Rochester
• Language: English
• Date: 2016-12-01
• Publisher: UBM Medica
• Publication Version: Author Accepted Manuscript (After Peer Review)
• Copyright Statement: © 2016 UBM Medica.
• Title of Journal or Parent Work: Oncology: New-York
• Volume: 30
• Issue: 12
• Start Page: 1099
• End Page: 1108
• Grant/Funding Information: None declared
• Keywords: Brentuximab vendotin; Stemm cell transplantation; Radiation-therapy; Life Sciences & Biomedicine; Science & Technology; High dose chemotherapy; Follow-up; Mantle irradiation; Prognostic significance; Involved field radiotherapy; Salvage therapy; Oncology; Phase II
• Research Categories: Biology, Cell; Health Sciences, Rehabilitation and Therapy; Health Sciences, Oncology; Health Sciences, Radiology

Abstract

This topic addresses the management of recurrent Hodgkin lymphoma. While autologous stem cell transplantation may be appropriate for select cases of recurrent disease following comprehensive combined-modality therapy, other options exist for patients treated with lower-dose therapy for early-stage disease. Additionally, innovative targeted therapies provide newer salvage options to consider. The American College of Radiology Appropriateness Criteria® are evidence-based guidelines for specific clinical conditions that are reviewed annually by a multidisciplinary expert panel. The guideline development and revision include an extensive analysis of current medical literature from peer-reviewed journals and the application of well-established methodologies (RAND/UCLA Appropriateness Method and Grading of Recommendations Assessment, Development, and Evaluation, or GRADE) to rate the appropriateness of imaging and treatment procedures for specific clinical scenarios. In those instances where evidence is lacking or equivocal, expert opinion may supplement the available evidence to recommend imaging or treatment. By combining the most recent medical literature and expert opinion, this revised guideline can aid clinicians in the complex decision-making associated with the management of recurrent Hodgkin lymphoma.