Interpreting biomonitoring data: Introducing the international human biomonitoring (i-HBM) working group's health-based guidance value (HB2GV) dashboard

• Type of Material: Article
• Authors: Shoji F Nakayama, National Institute for Environmental Studies, 16-2 Onogawa, Tsukuba, Ibaraki, 305-8506, Japan; Annie St-Amand, Health Canada; Tyler Pollock, Health Canada; Petra Apel, German Environment Agency, Berlin/ Dessau-Roßlau, Wörlitzer Platz 1, 06844, Dessau-Roßlau, Germany; Yu Ait Bamai, Hokkaido University; Dana Barr, Emory University; Jos Bessems, VITO NV; Antonia M Calafat, Centers for Disease Control and Prevention, Atlanta; Argelia Castaño, Inst Salud Carlos III; Adrian Covaci, University of Antwerp; Radu Corneliu Duca, Laboratoire national de santé, 1, Rue Louis Rech, L-3555, Dudelange, Luxembourg; Sarah Faure, Health Canada, Ottawa; Karen S Galea, Institute of Occupational Medicine (IOM), Research Avenue North, Riccarton, Edinburgh, EH14 4AP, UK; Sean Hays, Summit Toxicology LLP, 615 Nikles Dr., Unit 102, Bozeman, MT, 59715, USA; Nancy B Hopf, Center for Primary Care and Public Health, Route de la Corniche 2, 1066, Epalinges-Lausanne, Switzerland; Yuki Ito, Nagoya City University; Maryam Zare Jeddi, National Institute for Public Health and the Environment (RIVM), Antonie van Leeuwenhoeklaan 9, 3721 MA, Bilthoven, the Netherlands; Marike Kolossa-Gehring, German Environment Agency; Eva Kumar, Finnish Institute for Health and Welfare; Judy S LaKind, LaKind Associates LLC; Marta Esteban López, Instituto de Salud Carlos III; Henriqueta Louro, National Institute of Health Doutor Ricardo Jorge (INSA); Kristin Macey, Health Canada; Konstantinos C Makris, Cyprus University of Technology; Lisa Melnyk, U.S. Environmental Protection Agency, Office of Research and Development/Center for Public Health and Environmental Assessment, 26 West Martin Luther King Drive, Cincinnati, OH, 45268, USA; Aline Murawski, German Environment Agency; Josh Naiman, LaKind Associates LLC; Julianne Nassif, Association of Public Health Laboratories; Nolwenn Noisel, Université de Montréal; Devika Poddalgoda, Health Canada; Lesliam Quirós-Alcalá, Johns Hopkins Bloomberg School of Public Health; Ata Rafiee, University of Alberta; Loïc Rambaud, Santé publique France, 12 rue du Val d’Osne, 94415, Saint-Maurice, France; Maria João Silva, National Institute of Health Doutor Ricardo Jorge; Jun Ueyama, Nagoya University; Marc-Andre Verner, Université de Montréal; Maisarah N Waras, Universiti Sains Malaysia; Kate Werry, Health Canada
• Language: English
• Date: 2023-01-01
• Publisher: ELSEVIER GMBH
• Publication Version: Author Accepted Manuscript (After Peer Review)
• Copyright Statement: © 2022 Published by Elsevier GmbH.
• License: Creative Commons Attribution 4.0 International
• Final Published Version (URL): http://dx.doi.org/10.1016/j.ijheh.2022.114046
• Title of Journal or Parent Work: INTERNATIONAL JOURNAL OF HYGIENE AND ENVIRONMENTAL HEALTH
• Volume: 247
• Start Page: 114046
• End Page: 114046
• Keywords: Public, Environmental & Occupational Health; Science & Technology; GUIDELINES; EQUIVALENTS; Guidance values; BIOMARKER DATA; Biomonitoring equivalents; Biomonitoring; International society of exposure science; TRENDS; EXPOSURE ASSESSMENT; Reference values; Life Sciences & Biomedicine; POPULATION; RISK; Infectious Diseases

Abstract

Human biomonitoring (HBM) data measured in specific contexts or populations provide information for comparing population exposures. There are numerous health-based biomonitoring guidance values, but to locate these values, interested parties need to seek them out individually from publications, governmental reports, websites and other sources. Until now, there has been no central, international repository for this information. Thus, a tool is needed to help researchers, public health professionals, risk assessors, and regulatory decision makers to quickly locate relevant values on numerous environmental chemicals. A free, on-line repository for international health-based guidance values to facilitate the interpretation of HBM data is now available. The repository is referred to as the “Human Biomonitoring Health-Based Guidance Value (HB2GV) Dashboard”. The Dashboard represents the efforts of the International Human Biomonitoring Working Group (i-HBM), affiliated with the International Society of Exposure Science. The i-HBM's mission is to promote the use of population-level HBM data to inform public health decision-making by developing harmonized resources to facilitate the interpretation of HBM data in a health-based context. This paper describes the methods used to compile the human biomonitoring health-based guidance values, how the values can be accessed and used, and caveats with using the Dashboard for interpreting HBM data. To our knowledge, the HB2GV Dashboard is the first open-access, curated database of HBM guidance values developed for use in interpreting HBM data. This new resource can assist global HBM data users such as risk assessors, risk managers and biomonitoring programs with a readily available compilation of guidance values.