Obesity does not modify the effect of continuous positive airway pressure on insulin resistance in adults with obstructive sleep apnoea

• Type of Material: Article
• Authors: Victoria Pak, Emory University; David G. Maislin, University of Pennsylvania; Brendan T. Keenan, University of Pennsylvania; Xiaofeng Guo, University of Pennsylvania; Ray Townsend, University of Pennsylvania; Bryndis Benediktsdottir, Landspitali National University Hospital Iceland; Allan I. Pack, University of Pennsylvania; Thorarinn Gislason, Landspitali National University Hospital Iceland; Samuel T. Kuna, University of Pennsylvania
• Language: English
• Date: 2023-03-01
• Publisher: EUROPEAN RESPIRATORY SOC JOURNALS LTD
• Publication Version: Final Published Version
• Copyright Statement: ©The authors 2023
• License: Creative Commons Attribution-NonCommercial 4.0 International
• Final Published Version (URL): http://dx.doi.org/10.1183/23120541.00443-2022
• Title of Journal or Parent Work: ERJ OPEN RESEARCH
• Volume: 9
• Issue: 2
• Grant/Funding Information: This study was supported by grant P01-HL094307 from the National Heart, Lung, and Blood Institute (principal investigator: A.I. Pack).
• Keywords: Respiratory System; Life Sciences & Biomedicine; Science & Technology; GLUCOSE
• Research Categories: Health Sciences, Public Health; Health Sciences, Nutrition

Abstract

This study found no evidence that obesity significantly modifies the effect of 4 months of CPAP treatment on HOMA-IR. Longer duration of CPAP treatment may be needed in order to reduce insulin resistance and determine whether obesity modifies the effect. https://bit.ly/3CtX7jZ.