An Unusual Mimicker of Systemic Lupus Erythematosus: A Case Report

• Type of Material: Article
• Authors: Aloice O Aluoch, Emory University; Mathew Farbman, Emory University; Heather Gladue, Emory University
• Language: English
• Date: 2015
• Publisher: Bentham Open
• Publication Version: Final Published Version
• Copyright Statement: © Aluoch et al.
• License: Creative Commons Attribution-Noncommercial 3.0 Unported
• Final Published Version (URL): http://dx.doi.org/
• Title of Journal or Parent Work: Open Rheumatology Journal
• ISSN: 1874-3129
• Start Page: 27
• End Page: 29
• Keywords: antibodies; systemic lupus erythematosus; Adenocarcinoma; hypertrophic osteoarthropathy
• Research Categories: Health Sciences, General; Health Sciences, Medicine and Surgery

Abstract

We present a case of a 47 year-old African American female with 15 pack-years of tobacco use and heavy alcohol use who presented with arthritis and was found to have a positive antinuclear antibodies (ANA), anti double stranded DNA antibodies (anti-dsDNA), and anti-Sjogren’s syndrome-related antigen A and antigen B (anti-SSA and anti-SSB). She was subsequently found to have a lung adenocarcinoma associated with hypertrophic pulmonary osteoarthropathy (HPO). This demonstrates a case of positive antinuclear antibodies and arthritis in a patient with lung adenocarcinoma, which can be falsely diagnosed as systemic lupus erythematosus.