DNA-Grafted 3D Superlattice Self-Assembly

• Type of Material: Article
• Authors: Shuang Wang, Nanjing University; Xiaolin Xie, Nanjing University; Zhi Chen, Nanjing University; Ningning Ma, Nanjing University; Xue Zhang, Nanjing University; Kai Li, Nanjing University; Chao Teng, Shenzhen Polytechnic; Yonggang Ke, Emory University; Ye Tian, Nanjing University
• Language: English
• Date: 2021-07-15
• Publisher: MDPI AG
• Publication Version: Final Published Version
• Copyright Statement: © 2021 by the authors.
• License: Creative Commons Attribution 4.0 International
• Final Published Version (URL): http://dx.doi.org/10.3390/ijms22147558
• Title of Journal or Parent Work: INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
• Volume: 22
• Issue: 14
• Grant/Funding Information: This work is supported by Shenzhen International Cooperation Research Project (No. GJHZ20180930090602235, GJHZ20190819151807167). It is also supported by the Post-doctoral Foundation Project of Shenzhen Polytechnic (grant no.6021330004K, 6020330008K0), Shenzhen Science and Technology Innovation Commission (JSGG20200103094001790), Guang-dong Basic and Applied Basic Research Foundation (grant no. 2020A1515110107) and China Postdoctoral Science Foundation (grant no. 2020M671437).
• Keywords: DNA tile; DNA nanotechnology; DNA origami; superlattice; self-assembly
• Research Categories: Biology, Genetics

Abstract

The exploitation of new methods to control material structure has historically been dominating the material science. The bottom-up self-assembly strategy by taking atom/molecule/ensembles in nanoscale as building blocks and crystallization as a driving force bring hope for material fabrication. DNA-grafted nanoparticle has emerged as a “programmable atom equivalent” and was employed for the assembly of hierarchically ordered three-dimensional superlattice with novel properties and studying the unknown assembly mechanism due to its programmability and versatility in the binding capabilities. In this review, we highlight the assembly strategies and rules of DNA-grafted three-dimensional superlattice, dynamic assembly by different driving factors, and discuss their future applications.