Neonatal Infectious Diseases: Evaluation of Neonatal Sepsis

• Type of Material: Article
• Authors: Andres Camacho-Gonzalez, Emory University; Paul Spearman, Emory University; Barbara Stoll, Emory University
• Language: English
• Date: 2013-04-01
• Publisher: Elsevier: 12 months
• Publication Version: Author Accepted Manuscript (After Peer Review)
• Copyright Statement: © 2013 Elsevier Inc.
• License: Creative Commons Attribution-NonCommercial-NoDerivs 4.0 International
• Final Published Version (URL): http://dx.doi.org/10.1016/j.pcl.2012.12.003
• Title of Journal or Parent Work: Pediatric Clinics of North America
• ISSN: 0031-3955
• Volume: 60
• Issue: 2
• Start Page: 367
• End Page: +
• Keywords: Neonatal sepsis; INTENSIVE-CARE-UNIT; C-REACTIVE PROTEIN; EMPIRICAL ANTIBIOTIC-TREATMENT; NOSOCOMIAL INFECTIONS; TOTAL PARENTERAL-NUTRITION; Immature immunity; Treatment; Early and late onset disease; Pediatrics; EARLY-ONSET SEPSIS; PRETERM INFANTS; ESCHERICHIA-COLI; Life Sciences & Biomedicine; Biologic markers; Science & Technology; STAPHYLOCOCCUS-AUREUS BACTEREMIA; B STREPTOCOCCAL DISEASE
• Research Categories: Health Sciences, Immunology

Abstract

Neonatal sepsis remains a feared cause of morbidity and mortality in the neonatal period. Maternal, neonatal, and environmental factors are associated with risk of infection, and a combination of prevention strategies, judicious neonatal evaluation, and early initiation of therapy are required to prevent adverse outcomes. This article reviews recent trends in epidemiology and provides an update on risk factors, diagnostic methods, and management of neonatal sepsis.