The neural control of heartbeat in invertebrates

• Type of Material: Article
• Authors: Ronald Calabrese, Emory University; Brian Norris, Emory University; Angela Wenning, Emory University
• Language: English
• Date: 2016-12-01
• Publisher: Elsevier: 12 months
• Publication Version: Author Accepted Manuscript (After Peer Review)
• Copyright Statement: © 2016 Elsevier Ltd. All rights reserved.
• Final Published Version (URL): http://dx.doi.org/10.1016/j.conb.2016.08.004
• Title of Journal or Parent Work: Current Opinion in Neurobiology
• ISSN: 0959-4388
• Volume: 41
• Start Page: 68
• End Page: 77
• Grant/Funding Information: Supported by NIH NINDS 1 R01 NS085006
• Research Categories: Biology, General; Biology, Neuroscience

Abstract

The neurogenic heartbeat of certain invertebrates has long been studied both as a way of understanding how automatic functions are regulated and for how neuronal networks generate the inherent rhythmic activity that controls and coordinates this vital function. This review focuses on the heartbeat of decapod crustaceans and hirudinid leeches, which remain important experimental systems for the exploration of central pattern generator networks, their properties, network and cellular mechanisms, modulation, and how animal-to-animal variation in neuronal and network properties are managed to produce functional output.