PrEParing for long-acting injectable PrEP in the South: perspectives from healthcare providers in Georgia

• Type of Material: Article
• Authors: Casey D Xavier Hall, Northwestern University; Justin C Smith, Emory University; Robert A Driggers, Emory University; Bethany Stoller, Emory University; Zara Khan, Emory University; Jingjing Li, Emory University; Elisa H Ignatius, Johns Hopkins University; Aaron Siegler, Emory University
• Language: English
• Date: 2020-08-27
• Publisher: ROUTLEDGE JOURNALS, TAYLOR & FRANCIS LTD
• Publication Version: Author Accepted Manuscript (After Peer Review)
• Copyright Statement: Rights managed by Taylor & Francis
• License: Creative Commons Attribution-NonCommercial 4.0 International
• Final Published Version (URL): http://dx.doi.org/10.1080/09540121.2020.1810616
• Title of Journal or Parent Work: AIDS CARE-PSYCHOLOGICAL AND SOCIO-MEDICAL ASPECTS OF AIDS/HIV
• Volume: 33
• Issue: 6
• Start Page: 706
• End Page: 711
• Grant/Funding Information: Emory University, Health Innovations Program Grant
• Keywords: Social Sciences, Biomedical; Biomedical Social Sciences; Life Sciences & Biomedicine; South; Respiratory System; Health Care Sciences & Services; healthcare provider; Social Sciences; Science & Technology; Psychology; Psychology, Multidisciplinary; Health Policy & Services; Public, Environmental & Occupational Health; PrEP

Abstract

New modalities of Pre-exposure Prophylaxis (PrEP) such as long-acting injectable PrEP (LAI-PrEP) promise increased prevention of HIV transmission; however, similar biomedical interventions have not been met with universal adoption by healthcare providers or populations most affected by HIV. This qualitative study explores healthcare provider considerations for the rollout of LAI-PrEP. Eleven key-informant in-depth interviews were conducted with clinicians who prescribe daily oral PrEP. Participants reviewed a currently proposed LAI regimen and were asked to reflect on its implications for their clinical practice. Interviews were transcribed verbatim and thematically coded, with results organized using the Consolidated Framework for Implementation Research (CFIR). All participants expressed interest in prescribing LAI-PrEP and anticipated that at least some patients would be interested. Participants identified characteristics of the intervention, inner intervention setting, and outer intervention setting that will be influential in bringing LAI-PrEP to scale. Clinicians in the South have unique insights into the challenges of and opportunities for successful rollout of future PrEP regimens. Bringing these insights into a CFIR framework highlights the nuances surrounding LAI-PrEP, including structural concerns such as cost barriers and access to in-person healthcare services. It is critical to address these challenges to ensure successful implementation of new PrEP formulations.