Arrhythmia Monitoring and Outcomes in Patients With Cardiac Sarcoidosis: Insights From the Cardiac Sarcoidosis Consortium

• Type of Material: Article
• Authors: Edoardo Bressi, Virginia Commonwealth University; Thomas C Crawford, University of Michigan Health System; Frank M Bogun, University of Michigan Health System; Xiaokui Gu, University of Michigan Health System; Kenneth A Ellenbogen, Virginia Commonwealth University; Alexandra B Chicos, Northwestern University; Henri Roukoz, University of Minnesota Minneapolis; Peter J Zimetbaum, Beth Israel Deaconess Medical Center; Steven J Kalbfleisch, Ohio State University; Francis D Murgatroyd, King's College Hospital, NHS Foundation Trust; David A Steckman, Albany Medical Center; Lynda E Rosenfeld, Yale University; Ann C Garlitski, Tufts University; Kyoko Soejima, Kyorin University; Adarsh K Bhan, Advocate Christ Medical Center; Vasanth Vedantham, University of California San Francisco; Timm M Dickfeld, University of Maryland, Baltimore; David De Lurgio, Emory University; Pyotr G Platonov, Lund University; Matthew M Zipse, University of Colorado Anschutz Medical Campus; Suguru Nishiuchi, Tenri Hospital; Matthew L Ortman, Rowan University; Calambur Narasimhan, AIG Hospitals; Kris K Patton, University of Washington; David G Rosenthal, University of California San Francisco; Siddharth S Mukerji, Memorial Hermann Heart & Vascular Institute, Houston; Jarieke C Hoogendoorn, Leiden University Medical Center; Katja Zeppenfeld, Leiden University Medical Center; William H Sauer, Brigham and Women's Hospital; Jordana Kron, Virginia Commonwealth University
• Language: English
• Date: 2022-07-05
• Publisher: WILEY
• Publication Version: Final Published Version
• Copyright Statement: © 2022 The Authors. Published on behalf of the American Heart Association, Inc., by Wiley.
• License: Creative Commons Attribution-NonCommercial-NoDerivs 4.0 International
• Final Published Version (URL): http://dx.doi.org/10.1161/JAHA.121.024924
• Title of Journal or Parent Work: JOURNAL OF THE AMERICAN HEART ASSOCIATION
• Volume: 11
• Issue: 13
• Start Page: e024924
• End Page: e024924
• Grant/Funding Information: Dr Platonov’s cardiac sarcoid research program is funded by The Swedish Heart‐Lung Foundation and the Skåne University Hospital.; Dr Kron was supported by CTSA award No. UL1TR002649 from the National Center for Advancing Translational Sciences. Its contents are solely the responsibility of the authors and do not necessarily represent official views of the National Center for Advancing Translational Sciences or the National Institutes of Health.
• Keywords: Cardiac & Cardiovascular Systems; Cardiovascular System & Cardiology; cardiac sarcoidosis; Holter monitoring; Science & Technology; arrhythmias; Life Sciences & Biomedicine; risk stratification; implantable cardioverter-defibrillator
• Research Categories: Health Sciences, Medicine and Surgery

Abstract

Arrhythmic risk stratification is essential in cardiac sarcoidosis (CS) but remains challenging because of the disease's unpredictable dynamic inflammatory nature. 1 Therefore, our goal was to describe the arrhythmia burden and outcomes in a large prospective cohort of patients from the CSC (Cardiac Sarcoidosis Consortium). The CSC, an international collaborative research group committed to deepening the understanding of CS, has more than 25 participating sarcoidosis centers in the United States, India, Japan, United Kingdom, Sweden, and the Netherlands. Data are collected annually in a prospective secure, web‐based registry managed at the University of Michigan. The data that support the findings of this study are available from the corresponding author upon reasonable request. Institutional review board approval was obtained from each institution and informed written consent was obtained from each patient.