Publication

American Association of Clinical Endocrinology Clinical Practice Guideline: Developing a Diabetes Mellitus Comprehensive Care Plan—2022 Update

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Last modified
  • 09/24/2025
Type of Material
Authors
    Priyathama Vellanki, Emory UniversitySuchitra Chandrasekaran, Emory UniversityLawrence Blonde, Ochsner HealthGuillermo Umpierrez, Emory UniversitySethu S Reddy, Central Michigan UniversityJanet B McGill, Washington University in St. LouisSarah L Berga, University at Buffalo, The State University of New YorkMichael Bush, Cedars-Sinai, Beverly Hills, CaliforniaRalph A DeFronzo, The University of Texas at San AntonioDaniel Einhorn, Whittier Institute for DiabetesRodolfo Galindo, Emory UniversityThomas W Gardner, University of Michigan, Ann ArborRajesh Garg, Harbor-UCLA Medical CenterTimothy W Garvey, The University of Alabama at BirminghamIrl B Hirsch, University of WashingtonDaniel L Hurley, Mayo Clinic, RochesterKenneth Izuora, University of Nevada, Las VegasMikhail Kosiborod, Mid America Heart Institute - Kansas CityDarin Olson, Emory UniversityShailendra B Patel, University of Cincinnati Medical CenterRodica Pop-Busui, University of Michigan, Ann ArborArchana R Sadhu, Houston MethodistSusan L Samson, Mayo Clinic in Jacksonville, FloridaCarla Stec, American Association of Clinical EndocrinologyWilliam V Tamborlane, Yale School of MedicineKatherine R Tuttle, University of WashingtonChristine Twining, Maine Medical CenterAdrian Vella, Mayo Clinic, RochesterSandra L Weber, University of South Carolina School of Medicine Greenville
Language
  • English
Date
  • 2022-10-01
Publisher
  • Elsevier
Publication Version
Copyright Statement
  • © 2022 AACE. Published by Elsevier Inc. All rights reserved.
Final Published Version (URL)
Title of Journal or Parent Work
Volume
  • 28
Issue
  • 10
Start Page
  • 923
End Page
  • 1049
Supplemental Material (URL)
Abstract
  • Objective: The objective of this clinical practice guideline is to provide updated and new evidence-based recommendations for the comprehensive care of persons with diabetes mellitus to clinicians, diabetes-care teams, other health care professionals and stakeholders, and individuals with diabetes and their caregivers. Methods: The American Association of Clinical Endocrinology selected a task force of medical experts and staff who updated and assessed clinical questions and recommendations from the prior 2015 version of this guideline and conducted literature searches for relevant scientific papers published from January 1, 2015, through May 15, 2022. Selected studies from results of literature searches composed the evidence base to update 2015 recommendations as well as to develop new recommendations based on review of clinical evidence, current practice, expertise, and consensus, according to established American Association of Clinical Endocrinology protocol for guideline development. Results: This guideline includes 170 updated and new evidence-based clinical practice recommendations for the comprehensive care of persons with diabetes. Recommendations are divided into four sections: (1) screening, diagnosis, glycemic targets, and glycemic monitoring; (2) comorbidities and complications, including obesity and management with lifestyle, nutrition, and bariatric surgery, hypertension, dyslipidemia, retinopathy, neuropathy, diabetic kidney disease, and cardiovascular disease; (3) management of prediabetes, type 2 diabetes with antihyperglycemic pharmacotherapy and glycemic targets, type 1 diabetes with insulin therapy, hypoglycemia, hospitalized persons, and women with diabetes in pregnancy; (4) education and new topics regarding diabetes and infertility, nutritional supplements, secondary diabetes, social determinants of health, and virtual care, as well as updated recommendations on cancer risk, nonpharmacologic components of pediatric care plans, depression, education and team approach, occupational risk, role of sleep medicine, and vaccinations in persons with diabetes. Conclusions: This updated clinical practice guideline provides evidence-based recommendations to assist with person-centered, team-based clinical decision-making to improve the care of persons with diabetes mellitus.
Author Notes
  • American Association of Clinical Endocrinology, 7643 Gate Parkway, Suite 104-328, Jacksonville, Florida 32256. Email: publications@aace.com
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