Endoscopic resection for early-stage esophageal cancer, are we there for squamous as well?

• Type of Material: Article
• Authors: Rushikesh Shah, Emory University; Field Willingham, Emory University
• Language: English
• Date: 2017-12-14
• Publisher: Nature Publishing Group
• Publication Version: Final Published Version
• Copyright Statement: © 2017 The Author(s)
• License: Creative Commons Attribution-NonCommercial-NoDerivs 4.0 International
• Final Published Version (URL): http://dx.doi.org/10.1038/ctg.2017.56
• Title of Journal or Parent Work: Clinical and Translational Gastroenterology
• ISSN: 2155-384X
• Volume: 8
• Issue: 12
• Start Page: e130
• End Page: e130
• Research Categories: Health Sciences, Medicine and Surgery

Abstract

Superficial esophageal squamous cell cancer (SESCC) is often managed with esophagectomy with or without chemoradiotherapy. Esophagectomy has a significant complication rate and is not an option for many patients. In the current issue, a retrospective single center study evaluated 66 patients with SESCC. With endoscopic resection followed by adjuvant chemoradiotherapy, the reported 1-, 3- and 5-year overall survival rates were 98%, 87% and 75% respectively, comparable to survival rates after esophagectomy or definitive chemoradiotherapy. This study suggests a key role for endoscopic management in SESCC, and provides important data on the combination of endoscopic management plus adjuvant chemoradiation.