Healthcare resource use among solid organ transplant recipients hospitalized with COVID-19

• Type of Material: Article
• Authors: Madeleine R. Heldman, University of Washington; Olivia S. Kates, University of Washington; Brandy M. Haydel, Icahn School of Medicine at Mount Sinai; Sander S. Florman, Icahn School of Medicine at Mount Sinai; Meenakshi M. Rana, Icahn School of Medicine at Mount Sinai; Zohra S. Chaudhry, Henry Ford Health System; Mayur S. Ramesh, Henry Ford Health System; Kassem Safa, Massachusetts General Hospital; Camille N. Kotton, Massachusetts General Hospital; Emily A. Blumberg, University of Pennsylvania; Behdad D. Besharatian, University of Pennsylvania; Sajal D. Tanna, Northwestern University; Michael G. Ison, Northwestern University; Maricar Malinis, Yale University; Marwan Azar, Yale University; Robert Rakita, University of Washington; Jose A. Morillas, Cleveland Clinic Foundation; Aneela Majeed, Cleveland Clinic Foundation; Afrah S. Sait, Johns Hopkins University; Mario Spaggiari, University of Illinois at Chicago; Vagish Hemmige, Albert Einstein College of Medicine of Yeshiva University; Sapna A. Mehta, NYU Langone Health; Henry Neumann, NYU Langone Health; Abbasali Badami, SUNY Downstate Health Sciences University; Amy Jeng, SUNY Downstate Health Sciences University; Jason D. Goldman, University of Washington; Anuradha Lala, Icahn School of Medicine at Mount Sinai; Marion Hemmersbach-Miller, Baylor College of Medicine; Margaret McCort, Albert Einstein College of Medicine of Yeshiva University; Valida Bajrovic, University of Colorado Anschutz Medical Campus; Carlos Ortiz-Bautista, Hospital General Universitario Gregorio Marañon; Rachel Friedman-Moraco, Emory University; Sameep Sehgal, Temple University; Erika D. Lease, University of Washington; Ajit P. Limaye, University of Washington; Cynthia E. Fisher, University of Washington
• Language: English
• Date: 2021-02-01
• Publisher: Wiley
• Publication Version: Final Published Version
• Copyright Statement: © 2021 John Wiley & Sons, Inc. All rights reserved
• License: Creative Commons Attribution 4.0 International
• Final Published Version (URL): http://dx.doi.org/10.1111/ctr.14174
• Title of Journal or Parent Work: Clinical Transplantation
• Volume: 35
• Issue: 2
• Start Page: e14174
• End Page: e14174
• Grant/Funding Information: This work was supported by the National Institute of Allergy and Infectious Diseases of the National Institutes of Health (T32AI118690 to MRH and OSK and HL143050 to CEF).
• Keywords: Organ Transplantation; Transplant Recipients; COVID-19; Humans; United States; Inpatients; Health Resources; Pandemics
• Research Categories: Health Sciences, Public Health; Health Sciences, Medicine and Surgery; Health Sciences, Health Care Management; Health Sciences, Epidemiology

Abstract

While recent data demonstrate similar mortality among solid organ transplant recipients (SOTR) and non‐transplant recipients with COVID‐19, 1 , 2 the magnitude of healthcare resource utilization by SOTR with COVID‐19 is incompletely described. Knowledge of hospital length of stay (LOS), intensive care unit (ICU) LOS, and duration of mechanical ventilation (MV) is essential for transplant centers to make informed decisions on resource allocation during surges in COVID‐19. Several studies have described these measures but are limited by small sample size, short or variable durations of follow‐up, or single‐center experiences. 2 , 3 , 4 A recent multicenter study by Coll et al reports on hospital LOS in SOTR with COVID‐19, but follow‐up time was not standardized and neither MV duration nor ICU LOS was measured. 4 To address these limitations, we performed analyses from data in a prospective, multicenter registry of 376 SOTR hospitalized with COVID‐19 with standardized 28‐day follow‐up, which has been previously described. 1