MomsTalkShots: An individually tailored educational application for maternal and infant vaccines

• Type of Material: Article
• Authors: Daniel A. Salmon, Johns Hopkins University; Rupali J. Limaye, Johns Hopkins University; Matthew Z. Dudley, Johns Hopkins University; Oladeji K. Oloko, Johns Hopkins University; Cathy Church-Balin, Johns Hopkins University; Mallory K. Ellingson, Emory University; Christine I. Spina, University of Colorado; Sarah E. Brewer, University of Colorado; Walter Orenstein, Emory University; Neal A. Halsey, Johns Hopkins University; Allison Chamberlain, Emory University; Robert Bednarczyk, Emory University; Fauzia Malik, Emory University; Paula Frew, Emory University; Sean T. O'Leary, University of Colorado; Saad Omer, Emory University
• Language: English
• Date: 2019-10-08
• Publisher: Elsevier Science Ltd.
• Publication Version: Author Accepted Manuscript (After Peer Review)
• Copyright Statement: © 2019 Elsevier Ltd. All rights reserved.
• License: Creative Commons Attribution-NonCommercial-NoDerivs 4.0 International
• Final Published Version (URL): http://dx.doi.org/10.1016/j.vaccine.2019.08.080
• Title of Journal or Parent Work: Vaccine
• Volume: 37
• Issue: 43
• Start Page: 6478
• End Page: 6485
• Grant/Funding Information: D Salmon received consulting and/or research support form Merck, Walgreens and Pfizer.; M Dudley received some support from Walgreens.; N Halsey served on one day advisory committees for Pfizer and Sanofi Pasteur; he serves on safety monitoring committees for an experimental Norovirus vaccine developed by Takeda and HPV vaccines developed by Merck; he also serves on advisory boards for a Lyme disease vaccine developed by Valneva and a live pertussis vaccine developed by ILiAD Biotechnologies.; A Chamberlain received paid consultancy with the American College of Obstetricians and Gynecologists regarding provider-to-patient communications.; This work was supported in part by the National Institutes of Health [grant number R01AI110482].
• Keywords: Research & Experimental Medicine; Nonmedical exemptions; School immunization requirements; Attitudes; Immunology; Science & Technology; Technology; Infection; Hesitancy; Vaccine hesitancy; Life Sciences & Biomedicine; Parental refusal; Pertussis; Consequences; Vaccine uptake; Risk; Vaccination; Medicine, Research & Experimental
• Research Categories: Health Sciences, Public Health; Health Sciences, Immunology; Health Sciences, Epidemiology

Abstract

Introduction. The development and initial assessment in a clinical setting of a theory-driven, individually tailored educational application (app), MomsTalkShots, focused on increasing uptake of maternal and infant vaccines is described. Methods. MomsTalkShots algorithmically tailored videos based on parent needs to deliver an intervention that was specifically responsive to individual vaccine attitudes, beliefs and intentions, demographics, and source credibility. MomsTalkShots was evaluated among 1,103 pregnant women recruited from 23 geographically and socio-demographically diverse obstetrician-gynecologist offices in Georgia and Colorado in 2017. Self-reported information needs were assessed pre-and post-videos and participants self-reported factors related to usability and analyzed in 2018. Results. The vast majority of women reported MomsTalkShots was helpful (95%), trustworthy (94%), interesting (97%) and clear to understand (99%), none of which varied by demographics or parity. Reported usability was slightly lower among vaccine hesitant women, yet the majority reported MomsTalkShots was helpful (91%), trustworthy (85%), interesting (97%) and clear (99%). The majority of women (72%) who did not have enough vaccine information pre-videos reported enough information post-videos. Conclusions. MomsTalkShots was designed to provide individually tailored vaccine information to pregnant women from a population with varied vaccine intentions, confidence and vaccine concerns. MomsTalkShots was extremely well-received among pregnant women, even among women who were initially vaccine hesitant and did not intend to vaccinate themselves and their infants according to the recommended immunization schedule. Next steps include evaluation to assess impact on vaccine uptake and expansion to adolescent and adult vaccines.