The Infant Aphakia Treatment Study Contact Lens Experience: One-Year Outcomes

• Type of Material: Article
• Authors: Buddy Russell, Emory University; Michael A Ward, Emory University; Michael Lynn, Emory University; Lindreth G Dubois, Emory University; Scott Lambert, Emory University
• Language: English
• Date: 2012-07-01
• Publisher: Lippincott, Williams & Wilkins
• Publication Version: Author Accepted Manuscript (After Peer Review)
• Copyright Statement: © 2012 Lippincott Williams & Wilkins.
• Final Published Version (URL): http://dx.doi.org/10.1097/ICL.0b013e3182562dc0
• Title of Journal or Parent Work: Eye and Contact Lens
• ISSN: 1542-2321
• Volume: 38
• Issue: 4
• Start Page: 234
• End Page: 239
• Grant/Funding Information: Supported by National Institutes of Health Grants U10 EY13272 and U10 EY013287 and in part by NIH Departmental Core Grant EY06360 and Research to Prevent Blindness, Inc., New York, New York
• Keywords: MANAGEMENT; Ophthalmology; EYES; CHILDREN; DAMAGE; Life Sciences & Biomedicine; Contact lens; Aphakia; Cataract; Science & Technology; UNILATERAL CONGENITAL CATARACTS; Infant; MONOCULAR CATARACTS; PEDIATRIC APHAKIA
• Research Categories: Health Sciences, Public Health; Health Sciences, General

Abstract

PURPOSE:: We describe our experience correcting a cohort of infants with contact lenses in the Infant Aphakia Treatment Study. MATERIALS AND METHODS:: Fifty-seven infants 1-6 months of age were randomized to contact lens wear. An examination under anesthesia was performed at the time of enrollment and at approximately 1 year of age. A traveling examiner assessed visual acuity at approximately 1 year of age. RESULTS:: Forty-two treated eyes (74 %) were fitted with silicone elastomer (SE) contact lenses; 12 eyes (21 %) with rigid gas permeable (RGP) contact lenses, and 3 eyes (5%) wore both lens types. Median visual acuity was +0.80 logMAR in both lens type-wearing groups. The mean (± SD) keratometric power of the treated eyes was 46.3±2.8 D at baseline and 44.6±2.3 D at 1 year of age for a mean decrease of 0.2±0.2 D/mo. Keratometric astigmatism of treated eyes was 1.98±1.37 D at baseline and 1.62±0.98 D at 1 year of age for a mean decrease of 0.05±0.2 D/mo. The mean RGP lens base curve at baseline was 47.62 D±2.62 D versus 47.00 D±3.50 D at 12 months after surgery. Children wearing SE lenses required a mean of 10.9 replacements (range 2-24) compared to 16.8 replacements (range 8-32) for children wearing RGP lenses. Three adverse events occurred. CONCLUSIONS:: Contact lenses were worn successfully with relatively few adverse events by a cohort of infants with unilateral aphakia. The visual acuity results were identical independent of the contact lens material or modality. RGP lenses needed replacement more often than SE lenses.