Biphasic Zika Illness With Rash and Joint Pain.

• Type of Material: Article
• Authors: Srilatha Edupuganti, Emory University; Muktha S. Natrajan, Emory University; Nadine Rouphael, Emory University; Lilin Lai, Emory University; Yongxian Xu, Emory University; Matthew Feldhammer, Emory University; Charles Hill, Emory University; Shital M. Patel, Baylor College of Medicine; Sara Jo Johnson, Emory University; Mary Bower, Emory University; Rodion Gorchakov, Baylor College of Medicine; Rebecca Berry, Baylor College of Medicine; Kristy O. Murray, Baylor College of Medicine; Mark Mulligan, Emory University
• Language: English
• Date: 2017-06-22
• Publisher: Oxford University Press (OUP)
• Publication Version: Final Published Version
• Copyright Statement: © The Author 2017.
• License: Creative Commons Attribution-NonCommercial-NoDerivs 4.0 International
• Final Published Version (URL): http://dx.doi.org/10.1093/ofid/ofx133
• Title of Journal or Parent Work: Open Forum Infectious Diseases
• ISSN: 2328-8957
• Volume: 4
• Issue: 3
• Start Page: ofx133
• End Page: ofx133
• Grant/Funding Information: This work was funded by the National Institutes of Health/National Institutes of Allergy and Infectious Diseases/Division of Microbiology and Infectious Diseases/Vaccine and Treatment Evaluation Units at Emory University (Contract No. HHSN272201300018I funding the DMID 16-0017 study) and at the Baylor College of Medicine (Contract No. HHSN27220130015I).; Additional funding was provided by the Georgia Research Alliance.
• Keywords: joint pains; rash; Zika illness; relapse
• Research Categories: Health Sciences, Pathology; Biology, Virology; Biology, Microbiology

Abstract

During the current Zika virus (ZIKV) outbreak, acute symptomatic ZIKV infection in adults appears to be a mild-to-moderate, self-limited illness. We present a case of ZIKV rash illness that improved and then relapsed without repeat exposure to ZIKV. Clinicians should be alert for relapses in patients with ZIKV infection.