Prevalence of various Human Papillomavirus (HPV) genotypes among women who subjected to routine Pap smear test in Bushehr city (South west of Iran) 2008-2009

• Type of Material: Article
• Authors: Keivan Zandi, Emory University; Seyed Sajjad Eghbali, Bushehr University of Mediccal Sciences; Rasool Hamkar, Tehran University of Medical Sciences; Shahnaz Ahmadi, Bushehr University of Mediccal Sciences; Elissa Ramedani, Bushehr University of Mediccal Sciences; Iman Deilami, Bushehr University of Mediccal Sciences; Heidar Aziz Nejad, Bushehr University of Mediccal Sciences; Fatemeh Farshadpour, Bushehr University of Mediccal Sciences; Zahra Rastian, Bushehr University of Mediccal Sciences
• Language: English
• Date: 2010-03-22
• Publisher: BioMed Central
• Publication Version: Final Published Version
• Copyright Statement: © 2010 Zandi et al; licensee BioMed Central Ltd.
• License: Creative Commons Attribution 2.0 Generic
• Final Published Version (URL): http://dx.doi.org/10.1186/1743-422X-7-65
• Title of Journal or Parent Work: Virology Journal
• ISSN: 1743-422X
• Volume: 7
• Issue: 1
• Start Page: 65
• End Page: 65
• Keywords: Life Sciences & Biomedicine; Virology; CERVICAL-CANCER; Science & Technology
• Research Categories: Health Sciences, Epidemiology; Health Sciences, Public Health

Abstract

Background. Some genotypes of human papillomaviruses can infect the genital tract and they are important infectious agents which their oncogenicity is regardable. Thus the aim of this study was to determine the prevalence of various genital human papillomaviruses (HPV) among women being subjected to routine pap smear test in Bushehr city of Iran. Results. Based on the collected data, 11(5.5%) samples were detected positive for HPV DNA and 189(94.5%) samples out of 200 samples were detected negative for HPV DNA. Meanwhile 4(2%) samples detected positive for HPV DNA by PCR were detected positive for HPV by pap smear test as well. On the other hand 5 samples which were detected positive for HPV by pap smear test didn't have HPV DNA after being tested by PCR method. Among the 11 positive samples 7 samples were identified as HPV-16, 3 samples were HPV-18 and one was HPV-53. Conclusion. Regarding the prevalence of highly carcinogen genotypes of HPV in our study determination of genital HPV prevalence among the normal population of women of Bushehr city is recommended.