PCR detection of the MspI polymorphism in the human IRBP gene (RPB3)

• Type of Material: Article
• Authors: Joy Wu, NIH; John Nickerson, Emory University
• Language: English
• Date: 1991-07-25
• Publisher: Oxford University Press (OUP): Policy C - Option B
• Publication Version: Final Published Version
• Copyright Statement: © 1991, Oxford University Press
• Final Published Version (URL): http://nar.oxfordjournals.org/content/19/14/4016.2.full.pdf+html?sid=10c3ac42-71ad-4255-a22e-74e9fdd521eb
• Title of Journal or Parent Work: Nucleic Acids Research
• ISSN: 0305-1048
• Volume: 19
• Issue: 14
• Start Page: 4016
• Research Categories: Health Sciences, Opthamology; Biology, Molecular

Abstract

The gene for interphotoreceptor retinoid-binding protein (IRBP) contains a Mspl and a Styl polymorphism near each other. Here we show the precise localization of the Mspl RFLP in Intron A at position 4591 relative to the Cap site, based on sequence analysis of PCR-amplified human genomic DNAs.